Genes from 10 Pathways and Significant Driver Genes included in SL prediction model*

GENE_SET	HALLMARK	BLCA	BRCA	CESC	COADREAD	GBM	HNSC	KIRC	LAML	LGG	LIHC	LUAD	LUSC	OV	PAAD	PRAD	SKCM	THCA	UCEC	UNIQUE_TOTAL
DRIVER_GENE		17	18	13	10	11	21	6	7	14	16	14	7	4	8	6	14	3	25	87
KEGG_APOPTOSIS	RESISTING CELL DEATH	6	14	6	2	4	14	5	1	3	8	6	4	1	2	5	35	0	26	53
KEGG_ECM_RECEPTOR_INTERACTION	ACTIVATING INVASION & METASTASIS	14	37	9	0	5	42	20	0	0	29	40	32	6	3	6	59	0	53	64
KEGG_FOCAL_ADHESION	SUSTAINING PROLIFERATIVE SIGNALING	23	68	21	1	11	84	29	0	4	47	70	52	8	6	13	135	2	107	158
KEGG_MAPK_SIGNALING_PATHWAY	SUSTAINING PROLIFERATIVE SIGNALING	10	38	19	2	7	70	20	2	3	31	36	27	3	9	5	126	4	92	166
KEGG_MTOR_SIGNALING_PATHWAY	SUSTAINING PROLIFERATIVE SIGNALING	2	10	6	1	3	16	4	0	2	10	11	4	0	1	2	22	1	20	34
KEGG_P53_SIGNALING_PATHWAY	GENOME INSTABILITY & MUTATION	7	12	5	1	3	16	8	1	2	9	6	6	1	2	4	22	1	19	37
KEGG_TGF_BETA_SIGNALING_PATHWAY	EVADING GROWTH SUPPRESSORS	2	2	2	0	0	10	1	0	0	4	4	2	0	2	1	9	0	12	18
REACTOME_CELL_CYCLE	SUSTAINING PROLIFERATIVE SIGNALING	25	55	21	2	6	59	24	5	1	37	36	34	3	3	10	94	0	134	196
REACTOME_DNA_REPAIR	GENOME INSTABILITY & MUTATION	9	20	6	0	1	22	10	0	0	13	10	6	2	0	3	6	0	37	44
REACTOME_PI3K_AKT_ACTIVATION	DEREGULATING CELLULAR ENERGETICS	3	11	6	1	3	7	6	0	3	9	5	3	0	1	4	13	0	13	22
UNIQUE_TOTAL		75	190	68	11	24	236	81	12	14	134	145	108	16	19	31	361	5	382	623

References:

1. Douglas Hanahan, Robert A. Weinberg. (2011) Hallmarks of Cancer: The Next Generation. Cell, 144(5), 646-674.
2. Subramanian, A., Tamayo, P. et al. (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting ge-nome-wide expression profiles. Proc Natl Acad Sci U S A. 102,15545-15550.
3. Bailey MH, Tokheim C et al. (2018) Comprehensive Characterization of Cancer Driver Genes and Mutations. Cell
4. Hallmarks of Cancer Panel Collection

Histology: BLCA; Pathway: KEGG_FOCAL_ADHESION; ; Total number of genes: 23

ARHGAP5 , COL11A1 , COL6A3 , COL6A6 , ERBB2 , FLNA , FN1 , ITGA11 , ITGA4 , KDR , LAMA2 , LAMA3 , LAMA4 , LAMA5 , MAPK9 , MET , MYLK , MYLK3 , PIK3CA , RELN , THBS2 , TNR , TNXB

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Histology: BLCA; Pathway: KEGG_ECM_RECEPTOR_INTERACTION; ; Total number of genes: 14

COL11A1 , COL6A3 , COL6A6 , FN1 , ITGA11 , ITGA4 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , RELN , THBS2 , TNR , TNXB

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Histology: BLCA; Pathway: KEGG_MAPK_SIGNALING_PATHWAY; ; Total number of genes: 10

CACNA1A , CACNA1G , CHUK , FGFR3 , FLNA , MAP3K13 , MAPK9 , NF1 , TAOK2 , TP53

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Histology: BLCA; Pathway: KEGG_TGF_BETA_SIGNALING_PATHWAY; ; Total number of genes: 2

CUL1 , THBS2

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Histology: BLCA; Pathway: KEGG_MTOR_SIGNALING_PATHWAY; ; Total number of genes: 2

PIK3CA , TSC1

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Histology: BLCA; Pathway: KEGG_APOPTOSIS; ; Total number of genes: 6

ATM , CASP8 , CHUK , DFFA , PIK3CA , TP53

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Histology: BLCA; Pathway: REACTOME_PI3K_AKT_ACTIVATION; ; Total number of genes: 3

CDKN1A , CHUK , PIK3CA

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Histology: BLCA; Pathway: KEGG_P53_SIGNALING_PATHWAY; ; Total number of genes: 7

ATM , CASP8 , CCNB3 , CDKN1A , CDKN2A , PIDD1 , TP53

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Histology: BLCA; Pathway: REACTOME_CELL_CYCLE; ; Total number of genes: 25

AKAP9 , ANAPC1 , ATM , BUB1 , BUB1B , CDC6 , CDKN1A , CDKN2A , CEP250 , CLIP1 , CUL1 , DIDO1 , DYNC1H1 , HSP90AA1 , MCM4 , MCM8 , POLE , PSME4 , RANBP2 , RB1 , REC8 , STAG2 , SYNE1 , SYNE2 , TP53

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Histology: BLCA; Pathway: REACTOME_DNA_REPAIR; ; Total number of genes: 9

ATM , BRCA2 , BRIP1 , ERCC2 , FANCD2 , MDC1 , POLE , PRKDC , REV3L

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Histology: BLCA; Pathway: DRIVER_GENE; ; Total number of genes: 17

ARID1A , ATM , CDKN2A , CREBBP , EP300 , ERBB2 , ERBB3 , ERCC2 , FBXW7 , FGFR3 , KDM6A , PIK3CA , PSIP1 , RB1 , SPTAN1 , TP53 , TSC1

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Histology: BLCA; Total number of genes: 75

AKAP9 , ANAPC1 , ARHGAP5 , ARID1A , ATM , BRCA2 , BRIP1 , BUB1 , BUB1B , CACNA1A , CACNA1G , CASP8 , CCNB3 , CDC6 , CDKN1A , CDKN2A , CEP250 , CHUK , CLIP1 , COL11A1 , COL6A3 , COL6A6 , CREBBP , CUL1 , DFFA , DIDO1 , DYNC1H1 , EP300 , ERBB2 , ERBB3 , ERCC2 , FANCD2 , FBXW7 , FGFR3 , FLNA , FN1 , HSP90AA1 , ITGA11 , ITGA4 , KDM6A , KDR , LAMA2 , LAMA3 , LAMA4 , LAMA5 , MAP3K13 , MAPK9 , MCM4 , MCM8 , MDC1 , MET , MYLK , MYLK3 , NF1 , PIDD1 , PIK3CA , POLE , PRKDC , PSIP1 , PSME4 , RANBP2 , RB1 , REC8 , RELN , REV3L , SPTAN1 , STAG2 , SYNE1 , SYNE2 , TAOK2 , THBS2 , TNR , TNXB , TP53 , TSC1

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Histology: BRCA; Pathway: KEGG_FOCAL_ADHESION; ; Total number of genes: 68

ACTB , ACTG1 , ACTN2 , ACTN4 , AKT3 , ARHGAP35 , ARHGAP5 , CAPN2 , COL11A1 , COL11A2 , COL1A2 , COL3A1 , COL4A1 , COL4A2 , COL4A4 , COL4A6 , COL5A1 , COL5A2 , COL6A1 , COL6A3 , COL6A6 , COMP , DIAPH1 , DOCK1 , ERBB2 , FLNA , FLNB , FLNC , FN1 , IGF1R , ITGA1 , ITGA10 , ITGA11 , ITGA8 , ITGB6 , ITGB7 , LAMA1 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , LAMB1 , LAMB2 , LAMB3 , LAMB4 , LAMC1 , MET , MYLK , PIK3CA , PIK3CB , PIK3R1 , PTEN , PTK2 , RAPGEF1 , RASGRF1 , RELN , ROCK2 , SOS2 , SRC , TLN1 , TLN2 , TNN , TNR , TNXB , VAV1 , VAV3 , VTN , VWF

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Histology: BRCA; Pathway: KEGG_ECM_RECEPTOR_INTERACTION; ; Total number of genes: 37

COL11A1 , COL11A2 , COL1A2 , COL3A1 , COL4A1 , COL4A2 , COL4A4 , COL4A6 , COL5A1 , COL5A2 , COL6A1 , COL6A3 , COL6A6 , COMP , FN1 , ITGA1 , ITGA10 , ITGA11 , ITGA8 , ITGB6 , ITGB7 , LAMA1 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , LAMB1 , LAMB2 , LAMB3 , LAMB4 , LAMC1 , RELN , TNN , TNR , TNXB , VTN , VWF

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Histology: BRCA; Pathway: KEGG_TGF_BETA_SIGNALING_PATHWAY; ; Total number of genes: 2

COMP , ROCK2

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Histology: BRCA; Pathway: KEGG_APOPTOSIS; ; Total number of genes: 14

AKT3 , APAF1 , ATM , BAX , BID , CAPN1 , CAPN2 , CASP8 , NTRK1 , PIK3CA , PIK3CB , PIK3R1 , RIPK1 , TP53

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Histology: BRCA; Pathway: KEGG_MAPK_SIGNALING_PATHWAY; ; Total number of genes: 38

AKT3 , CACNA1A , CACNA1B , CACNA1C , CACNA1D , CACNA1E , CACNA1F , CACNA1G , CACNA1H , CACNA1I , CACNA1S , CACNA2D2 , CACNA2D3 , DUSP16 , FGFR2 , FLNA , FLNB , FLNC , MAP2K4 , MAP3K1 , MAP3K12 , MAP3K4 , MAP3K5 , MAP4K1 , MAP4K4 , MAPK8IP3 , NF1 , NFATC4 , NTRK1 , RAPGEF2 , RASGRF1 , RASGRF2 , RPS6KA1 , RPS6KA2 , RPS6KA6 , SOS2 , TAOK2 , TP53

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Histology: BRCA; Pathway: KEGG_P53_SIGNALING_PATHWAY; ; Total number of genes: 12

ADGRB1 , APAF1 , ATM , ATR , BAX , BID , CASP8 , CCNB3 , GTSE1 , PTEN , TP53 , TSC2

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Histology: BRCA; Pathway: REACTOME_PI3K_AKT_ACTIVATION; ; Total number of genes: 11

AKT3 , CDKN1B , IRS1 , MTOR , NTRK1 , PHLPP1 , PIK3CA , PIK3CB , PIK3R1 , PTEN , TSC2

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Histology: BRCA; Pathway: KEGG_MTOR_SIGNALING_PATHWAY; ; Total number of genes: 10

AKT3 , MTOR , PIK3CA , PIK3CB , PIK3R1 , RPS6KA1 , RPS6KA2 , RPS6KA6 , RPTOR , TSC2

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Histology: BRCA; Pathway: REACTOME_CELL_CYCLE; ; Total number of genes: 55

ACTR1A , AHCTF1 , AKAP9 , ALMS1 , ANAPC1 , ANAPC4 , ATM , ATR , BRCA1 , CDK5RAP2 , CDKN1B , CEP192 , CEP250 , CEP57 , CEP63 , CKAP5 , CLASP1 , CLIP1 , CNTRL , DIDO1 , DKC1 , DNA2 , DYNC1H1 , E2F1 , ERCC6L , HDAC1 , HJURP , KIF2B , KNTC1 , LIN54 , MCM4 , MIS18BP1 , NINL , NUP107 , OFD1 , PCM1 , PCNT , POLA1 , POLE , PSMD1 , RANBP2 , RB1 , SGO2 , SMC1B , SMC3 , STAG1 , STAG2 , SYCP1 , SYCP2 , SYNE1 , SYNE2 , TP53 , TUBGCP2 , TUBGCP6 , XPO1

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Histology: BRCA; Pathway: REACTOME_DNA_REPAIR; ; Total number of genes: 20

ATM , ATR , BRCA1 , BRCA2 , BRIP1 , DDB1 , ERCC6 , FANCD2 , FANCM , LIG3 , MRE11 , PALB2 , POLE , POLR2B , PRKDC , RAD50 , REV3L , TP53BP1 , USP1 , XPC

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Histology: BRCA; Pathway: DRIVER_GENE; ; Total number of genes: 18

ARID1A , BRCA1 , CASP8 , CBFB , CDH1 , CDKN1B , ERBB2 , FBXW7 , MAP2K4 , MAP3K1 , NF1 , PIK3CA , PIK3R1 , PTEN , PTPRD , RB1 , RUNX1 , TP53

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Histology: BRCA; Total number of genes: 190

ACTB , ACTG1 , ACTN2 , ACTN4 , ACTR1A , ADGRB1 , AHCTF1 , AKAP9 , AKT3 , ALMS1 , ANAPC1 , ANAPC4 , APAF1 , ARHGAP35 , ARHGAP5 , ARID1A , ATM , ATR , BAX , BID , BRCA1 , BRCA2 , BRIP1 , CACNA1A , CACNA1B , CACNA1C , CACNA1D , CACNA1E , CACNA1F , CACNA1G , CACNA1H , CACNA1I , CACNA1S , CACNA2D2 , CACNA2D3 , CAPN1 , CAPN2 , CASP8 , CBFB , CCNB3 , CDH1 , CDK5RAP2 , CDKN1B , CEP192 , CEP250 , CEP57 , CEP63 , CKAP5 , CLASP1 , CLIP1 , CNTRL , COL11A1 , COL11A2 , COL1A2 , COL3A1 , COL4A1 , COL4A2 , COL4A4 , COL4A6 , COL5A1 , COL5A2 , COL6A1 , COL6A3 , COL6A6 , COMP , DDB1 , DIAPH1 , DIDO1 , DKC1 , DNA2 , DOCK1 , DUSP16 , DYNC1H1 , E2F1 , ERBB2 , ERCC6 , ERCC6L , FANCD2 , FANCM , FBXW7 , FGFR2 , FLNA , FLNB , FLNC , FN1 , GTSE1 , HDAC1 , HJURP , IGF1R , IRS1 , ITGA1 , ITGA10 , ITGA11 , ITGA8 , ITGB6 , ITGB7 , KIF2B , KNTC1 , LAMA1 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , LAMB1 , LAMB2 , LAMB3 , LAMB4 , LAMC1 , LIG3 , LIN54 , MAP2K4 , MAP3K1 , MAP3K12 , MAP3K4 , MAP3K5 , MAP4K1 , MAP4K4 , MAPK8IP3 , MCM4 , MET , MIS18BP1 , MRE11 , MTOR , MYLK , NF1 , NFATC4 , NINL , NTRK1 , NUP107 , OFD1 , PALB2 , PCM1 , PCNT , PHLPP1 , PIK3CA , PIK3CB , PIK3R1 , POLA1 , POLE , POLR2B , PRKDC , PSMD1 , PTEN , PTK2 , PTPRD , RAD50 , RANBP2 , RAPGEF1 , RAPGEF2 , RASGRF1 , RASGRF2 , RB1 , RELN , REV3L , RIPK1 , ROCK2 , RPS6KA1 , RPS6KA2 , RPS6KA6 , RPTOR , RUNX1 , SGO2 , SMC1B , SMC3 , SOS2 , SRC , STAG1 , STAG2 , SYCP1 , SYCP2 , SYNE1 , SYNE2 , TAOK2 , TLN1 , TLN2 , TNN , TNR , TNXB , TP53 , TP53BP1 , TSC2 , TUBGCP2 , TUBGCP6 , USP1 , VAV1 , VAV3 , VTN , VWF , XPC , XPO1

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Histology: CESC; Pathway: KEGG_FOCAL_ADHESION; ; Total number of genes: 21

ARHGAP35 , COL11A2 , COL5A1 , COL6A3 , FLNA , FLNC , FLT1 , ITGA8 , ITGB4 , LAMA1 , LAMA4 , MAPK1 , MAPK9 , PIK3CA , PIK3R1 , PIK3R3 , PTEN , SOS1 , SOS2 , TNC , VWF

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Histology: CESC; Pathway: KEGG_ECM_RECEPTOR_INTERACTION; ; Total number of genes: 9

COL11A2 , COL5A1 , COL6A3 , ITGA8 , ITGB4 , LAMA1 , LAMA4 , TNC , VWF

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Histology: CESC; Pathway: KEGG_MAPK_SIGNALING_PATHWAY; ; Total number of genes: 19

CACNA1E , CACNA1F , CACNA1I , DUSP10 , FLNA , FLNC , KRAS , MAP3K14 , MAP3K4 , MAP3K5 , MAPK1 , MAPK9 , NF1 , RASA1 , RASGRP2 , SOS1 , SOS2 , TGFBR2 , TP53

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Histology: CESC; Pathway: KEGG_P53_SIGNALING_PATHWAY; ; Total number of genes: 5

ADGRB1 , ATM , PTEN , TP53 , TSC2

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Histology: CESC; Pathway: REACTOME_PI3K_AKT_ACTIVATION; ; Total number of genes: 6

MTOR , PHLPP1 , PIK3CA , PIK3R1 , PTEN , TSC2

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Histology: CESC; Pathway: KEGG_MTOR_SIGNALING_PATHWAY; ; Total number of genes: 6

MAPK1 , MTOR , PIK3CA , PIK3R1 , PIK3R3 , TSC2

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Histology: CESC; Pathway: KEGG_APOPTOSIS; ; Total number of genes: 6

ATM , MAP3K14 , PIK3CA , PIK3R1 , PIK3R3 , TP53

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Histology: CESC; Pathway: KEGG_TGF_BETA_SIGNALING_PATHWAY; ; Total number of genes: 2

MAPK1 , TGFBR2

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Histology: CESC; Pathway: REACTOME_CELL_CYCLE; ; Total number of genes: 21

AHCTF1 , ALMS1 , ATM , CDK5RAP2 , CEP164 , CLASP1 , CNTRL , DYNC1H1 , DYNC1I2 , DYRK1A , KNTC1 , POLE , PSME4 , RB1 , SGO2 , SYCP2 , SYNE1 , SYNE2 , TP53 , TUBGCP6 , ZWINT

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Histology: CESC; Pathway: REACTOME_DNA_REPAIR; ; Total number of genes: 6

ATM , BRIP1 , MDC1 , POLE , PRKDC , TP53BP1

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Histology: CESC; Pathway: DRIVER_GENE; ; Total number of genes: 13

ARID1A , EP300 , ERBB3 , FBXW7 , KRAS , LATS1 , MAPK1 , NOTCH1 , PIK3CA , PTEN , RB1 , TGFBR2 , TP53

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Histology: CESC; Total number of genes: 68

ADGRB1 , AHCTF1 , ALMS1 , ARHGAP35 , ARID1A , ATM , BRIP1 , CACNA1E , CACNA1F , CACNA1I , CDK5RAP2 , CEP164 , CLASP1 , CNTRL , COL11A2 , COL5A1 , COL6A3 , DUSP10 , DYNC1H1 , DYNC1I2 , DYRK1A , EP300 , ERBB3 , FBXW7 , FLNA , FLNC , FLT1 , ITGA8 , ITGB4 , KNTC1 , KRAS , LAMA1 , LAMA4 , LATS1 , MAP3K14 , MAP3K4 , MAP3K5 , MAPK1 , MAPK9 , MDC1 , MTOR , NF1 , NOTCH1 , PHLPP1 , PIK3CA , PIK3R1 , PIK3R3 , POLE , PRKDC , PSME4 , PTEN , RASA1 , RASGRP2 , RB1 , SGO2 , SOS1 , SOS2 , SYCP2 , SYNE1 , SYNE2 , TGFBR2 , TNC , TP53 , TP53BP1 , TSC2 , TUBGCP6 , VWF , ZWINT

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Histology: COADREAD; Pathway: KEGG_MTOR_SIGNALING_PATHWAY; ; Total number of genes: 1

PIK3CA

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Histology: COADREAD; Pathway: KEGG_APOPTOSIS; ; Total number of genes: 2

PIK3CA , TP53

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Histology: COADREAD; Pathway: KEGG_FOCAL_ADHESION; ; Total number of genes: 1

PIK3CA

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Histology: COADREAD; Pathway: REACTOME_PI3K_AKT_ACTIVATION; ; Total number of genes: 1

PIK3CA

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Histology: COADREAD; Pathway: KEGG_MAPK_SIGNALING_PATHWAY; ; Total number of genes: 2

KRAS , TP53

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Histology: COADREAD; Pathway: KEGG_P53_SIGNALING_PATHWAY; ; Total number of genes: 1

TP53

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Histology: COADREAD; Pathway: REACTOME_CELL_CYCLE; ; Total number of genes: 2

SYNE1 , TP53

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Histology: COADREAD; Pathway: DRIVER_GENE; ; Total number of genes: 10

ACVR2A , APC , ARID1A , FBXW7 , GNAS , KRAS , PIK3CA , SMAD2 , SMAD4 , TP53

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Histology: COADREAD; Total number of genes: 11

ACVR2A , APC , ARID1A , FBXW7 , GNAS , KRAS , PIK3CA , SMAD2 , SMAD4 , SYNE1 , TP53

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Histology: GBM; Pathway: KEGG_FOCAL_ADHESION; ; Total number of genes: 11

COL6A2 , COL6A3 , EGFR , LAMA1 , LAMA3 , PDGFRA , PIK3CA , PIK3CG , PIK3R1 , PTEN , RELN

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Histology: GBM; Pathway: KEGG_ECM_RECEPTOR_INTERACTION; ; Total number of genes: 5

COL6A2 , COL6A3 , LAMA1 , LAMA3 , RELN

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Histology: GBM; Pathway: KEGG_P53_SIGNALING_PATHWAY; ; Total number of genes: 3

ATR , PTEN , TP53

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Histology: GBM; Pathway: REACTOME_PI3K_AKT_ACTIVATION; ; Total number of genes: 3

PIK3CA , PIK3R1 , PTEN

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Histology: GBM; Pathway: KEGG_MAPK_SIGNALING_PATHWAY; ; Total number of genes: 7

CACNA1B , CACNA1S , CACNA2D1 , EGFR , NF1 , PDGFRA , TP53

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Histology: GBM; Pathway: KEGG_MTOR_SIGNALING_PATHWAY; ; Total number of genes: 3

PIK3CA , PIK3CG , PIK3R1

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Histology: GBM; Pathway: KEGG_APOPTOSIS; ; Total number of genes: 4

PIK3CA , PIK3CG , PIK3R1 , TP53

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Histology: GBM; Pathway: REACTOME_CELL_CYCLE; ; Total number of genes: 6

ATR , RB1 , SGO2 , STAG2 , SYNE1 , TP53

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Histology: GBM; Pathway: REACTOME_DNA_REPAIR; ; Total number of genes: 1

ATR

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Histology: GBM; Pathway: DRIVER_GENE; ; Total number of genes: 11

ATRX , EGFR , IDH1 , LZTR1 , NF1 , PDGFRA , PIK3CA , PIK3R1 , PTEN , RB1 , TP53

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Histology: GBM; Total number of genes: 24

ATR , ATRX , CACNA1B , CACNA1S , CACNA2D1 , COL6A2 , COL6A3 , EGFR , IDH1 , LAMA1 , LAMA3 , LZTR1 , NF1 , PDGFRA , PIK3CA , PIK3CG , PIK3R1 , PTEN , RB1 , RELN , SGO2 , STAG2 , SYNE1 , TP53

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Histology: HNSC; Pathway: KEGG_FOCAL_ADHESION; ; Total number of genes: 84

ACTN1 , ACTN2 , ACTN3 , AKT3 , ARHGAP35 , ARHGAP5 , BRAF , COL11A1 , COL11A2 , COL1A2 , COL3A1 , COL4A1 , COL4A2 , COL4A4 , COL4A6 , COL5A1 , COL5A2 , COL5A3 , COL6A1 , COL6A2 , COL6A3 , COL6A6 , DIAPH1 , DOCK1 , EGF , EGFR , ERBB2 , FLNA , FLNB , FLNC , FLT1 , FLT4 , FN1 , HGF , HRAS , ITGA10 , ITGA11 , ITGA4 , ITGA8 , ITGAV , ITGB1 , ITGB3 , ITGB6 , KDR , LAMA1 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , LAMB1 , LAMB4 , LAMC1 , LAMC2 , LAMC3 , MAPK1 , MYLK , PAK2 , PAK5 , PDGFD , PDGFRA , PDGFRB , PIK3CA , PIK3CG , PIK3R5 , PRKCA , PRKCG , PTEN , PTK2 , RAC1 , RASGRF1 , RELN , ROCK1 , ROCK2 , SOS1 , SOS2 , THBS1 , THBS2 , TLN1 , TLN2 , TNC , TNN , TNR , TNXB , VWF

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Histology: HNSC; Pathway: KEGG_ECM_RECEPTOR_INTERACTION; ; Total number of genes: 42

COL11A1 , COL11A2 , COL1A2 , COL3A1 , COL4A1 , COL4A2 , COL4A4 , COL4A6 , COL5A1 , COL5A2 , COL5A3 , COL6A1 , COL6A2 , COL6A3 , COL6A6 , FN1 , ITGA10 , ITGA11 , ITGA4 , ITGA8 , ITGAV , ITGB1 , ITGB3 , ITGB6 , LAMA1 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , LAMB1 , LAMB4 , LAMC1 , LAMC2 , LAMC3 , RELN , THBS1 , THBS2 , TNC , TNN , TNR , TNXB , VWF

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Histology: HNSC; Pathway: KEGG_TGF_BETA_SIGNALING_PATHWAY; ; Total number of genes: 10

CUL1 , E2F5 , MAPK1 , RBL1 , ROCK1 , ROCK2 , RPS6KB1 , TGFBR2 , THBS1 , THBS2

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Histology: HNSC; Pathway: KEGG_MTOR_SIGNALING_PATHWAY; ; Total number of genes: 16

AKT3 , BRAF , MAPK1 , MTOR , PIK3CA , PIK3CG , PIK3R5 , PRKAA1 , RICTOR , RPS6KA1 , RPS6KA2 , RPS6KA6 , RPS6KB1 , STRADA , TSC2 , ULK1

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Histology: HNSC; Pathway: KEGG_APOPTOSIS; ; Total number of genes: 14

AKT3 , APAF1 , ATM , CASP6 , CASP8 , CHUK , IKBKB , IL1RAP , IRAK3 , MAP3K14 , PIK3CA , PIK3CG , PIK3R5 , TP53

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Histology: HNSC; Pathway: KEGG_MAPK_SIGNALING_PATHWAY; ; Total number of genes: 70

AKT3 , BRAF , CACNA1A , CACNA1B , CACNA1C , CACNA1D , CACNA1E , CACNA1F , CACNA1G , CACNA1H , CACNA1I , CACNA1S , CACNA2D1 , CACNA2D4 , CACNB2 , CACNG4 , CACNG5 , CHUK , EGF , EGFR , FGFR3 , FGFR4 , FLNA , FLNB , FLNC , FOS , HRAS , HSPA1L , HSPA6 , HSPA8 , IKBKB , MAP3K1 , MAP3K12 , MAP3K13 , MAP3K14 , MAP3K4 , MAP3K6 , MAP3K7 , MAP4K1 , MAP4K4 , MAPK1 , MECOM , MEF2C , MOS , NF1 , NFATC2 , NFKB2 , PAK2 , PDGFRA , PDGFRB , PRKCA , PRKCG , RAC1 , RASA1 , RASA2 , RASGRF1 , RASGRF2 , RASGRP1 , RASGRP2 , RASGRP3 , RPS6KA1 , RPS6KA2 , RPS6KA5 , RPS6KA6 , SOS1 , SOS2 , TAB1 , TAOK2 , TGFBR2 , TP53

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Histology: HNSC; Pathway: KEGG_P53_SIGNALING_PATHWAY; ; Total number of genes: 16

APAF1 , ATM , ATR , CASP8 , CCNB3 , CDK4 , CDKN2A , CHEK2 , PTEN , SERPINE1 , SESN3 , SFN , SIAH1 , THBS1 , TP53 , TSC2

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Histology: HNSC; Pathway: REACTOME_PI3K_AKT_ACTIVATION; ; Total number of genes: 7

AKT3 , CHUK , MTOR , PIK3CA , PTEN , RICTOR , TSC2

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Histology: HNSC; Pathway: REACTOME_CELL_CYCLE; ; Total number of genes: 59

AHCTF1 , AKAP9 , ALMS1 , ANAPC1 , ATM , ATR , BRCA1 , BUB1B , CCNA1 , CDC27 , CDK4 , CDK5RAP2 , CDKN2A , CEP192 , CEP250 , CHEK2 , CKAP5 , CNTRL , CUL1 , DIDO1 , DYNC1H1 , DYRK1A , E2F5 , HIST1H2BD , HIST1H2BN , HSP90AA1 , KIF23 , KIF2B , KNL1 , KNTC1 , LIN54 , MCM2 , MCM7 , MCM8 , NEDD1 , NINL , NUMA1 , OFD1 , PCNT , POLD1 , POLE , POT1 , PSMC6 , PSME4 , RAD17 , RANBP2 , RB1 , RBL1 , SMC1B , SMC3 , STAG1 , SYCP1 , SYCP2 , SYNE1 , SYNE2 , TERF2 , TP53 , TUBGCP6 , ZW10

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Histology: HNSC; Pathway: REACTOME_DNA_REPAIR; ; Total number of genes: 22

ATM , ATR , BRCA1 , BRCA2 , BRIP1 , DDB1 , ERCC4 , ERCC5 , FANCD2 , LIG4 , MDC1 , PALB2 , POLD1 , POLE , POLR2A , POLR2B , PRKDC , RAD50 , REV3L , TDP1 , TP53BP1 , XAB2

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Histology: HNSC; Pathway: DRIVER_GENE; ; Total number of genes: 21

CASP8 , CDKN2A , CYLD , EP300 , EPHA2 , FBXW7 , FGFR3 , FLNA , HRAS , KDM6A , MAPK1 , MYH9 , NOTCH1 , NSD1 , PIK3CA , PTEN , RAC1 , RASA1 , RB1 , TGFBR2 , TP53

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Histology: HNSC; Total number of genes: 236

ACTN1 , ACTN2 , ACTN3 , AHCTF1 , AKAP9 , AKT3 , ALMS1 , ANAPC1 , APAF1 , ARHGAP35 , ARHGAP5 , ATM , ATR , BRAF , BRCA1 , BRCA2 , BRIP1 , BUB1B , CACNA1A , CACNA1B , CACNA1C , CACNA1D , CACNA1E , CACNA1F , CACNA1G , CACNA1H , CACNA1I , CACNA1S , CACNA2D1 , CACNA2D4 , CACNB2 , CACNG4 , CACNG5 , CASP6 , CASP8 , CCNA1 , CCNB3 , CDC27 , CDK4 , CDK5RAP2 , CDKN2A , CEP192 , CEP250 , CHEK2 , CHUK , CKAP5 , CNTRL , COL11A1 , COL11A2 , COL1A2 , COL3A1 , COL4A1 , COL4A2 , COL4A4 , COL4A6 , COL5A1 , COL5A2 , COL5A3 , COL6A1 , COL6A2 , COL6A3 , COL6A6 , CUL1 , CYLD , DDB1 , DIAPH1 , DIDO1 , DOCK1 , DYNC1H1 , DYRK1A , E2F5 , EGF , EGFR , EP300 , EPHA2 , ERBB2 , ERCC4 , ERCC5 , FANCD2 , FBXW7 , FGFR3 , FGFR4 , FLNA , FLNB , FLNC , FLT1 , FLT4 , FN1 , FOS , HGF , HIST1H2BD , HIST1H2BN , HRAS , HSP90AA1 , HSPA1L , HSPA6 , HSPA8 , IKBKB , IL1RAP , IRAK3 , ITGA10 , ITGA11 , ITGA4 , ITGA8 , ITGAV , ITGB1 , ITGB3 , ITGB6 , KDM6A , KDR , KIF23 , KIF2B , KNL1 , KNTC1 , LAMA1 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , LAMB1 , LAMB4 , LAMC1 , LAMC2 , LAMC3 , LIG4 , LIN54 , MAP3K1 , MAP3K12 , MAP3K13 , MAP3K14 , MAP3K4 , MAP3K6 , MAP3K7 , MAP4K1 , MAP4K4 , MAPK1 , MCM2 , MCM7 , MCM8 , MDC1 , MECOM , MEF2C , MOS , MTOR , MYH9 , MYLK , NEDD1 , NF1 , NFATC2 , NFKB2 , NINL , NOTCH1 , NSD1 , NUMA1 , OFD1 , PAK2 , PAK5 , PALB2 , PCNT , PDGFD , PDGFRA , PDGFRB , PIK3CA , PIK3CG , PIK3R5 , POLD1 , POLE , POLR2A , POLR2B , POT1 , PRKAA1 , PRKCA , PRKCG , PRKDC , PSMC6 , PSME4 , PTEN , PTK2 , RAC1 , RAD17 , RAD50 , RANBP2 , RASA1 , RASA2 , RASGRF1 , RASGRF2 , RASGRP1 , RASGRP2 , RASGRP3 , RB1 , RBL1 , RELN , REV3L , RICTOR , ROCK1 , ROCK2 , RPS6KA1 , RPS6KA2 , RPS6KA5 , RPS6KA6 , RPS6KB1 , SERPINE1 , SESN3 , SFN , SIAH1 , SMC1B , SMC3 , SOS1 , SOS2 , STAG1 , STRADA , SYCP1 , SYCP2 , SYNE1 , SYNE2 , TAB1 , TAOK2 , TDP1 , TERF2 , TGFBR2 , THBS1 , THBS2 , TLN1 , TLN2 , TNC , TNN , TNR , TNXB , TP53 , TP53BP1 , TSC2 , TUBGCP6 , ULK1 , VWF , XAB2 , ZW10

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Histology: KIRC; Pathway: KEGG_FOCAL_ADHESION; ; Total number of genes: 29

ARHGAP35 , ARHGAP5 , COL11A1 , COL2A1 , COL5A2 , COL5A3 , COL6A3 , COL6A6 , EGFR , FLNB , IGF1R , ITGA10 , ITGA11 , ITGAV , LAMA5 , LAMB1 , LAMC1 , LAMC2 , LAMC3 , MYLK , PIK3CA , PTEN , RELN , THBS1 , TLN2 , TNC , TNN , TNR , VWF

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Histology: KIRC; Pathway: KEGG_ECM_RECEPTOR_INTERACTION; ; Total number of genes: 20

COL11A1 , COL2A1 , COL5A2 , COL5A3 , COL6A3 , COL6A6 , ITGA10 , ITGA11 , ITGAV , LAMA5 , LAMB1 , LAMC1 , LAMC2 , LAMC3 , RELN , THBS1 , TNC , TNN , TNR , VWF

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Histology: KIRC; Pathway: KEGG_MAPK_SIGNALING_PATHWAY; ; Total number of genes: 20

ATF4 , CACNA1A , CACNA1C , CACNA1E , CACNA1G , CACNA1S , EGFR , FLNB , HSPA8 , IL1R2 , MAP3K1 , MAP3K5 , MAPK14 , NF1 , NTRK1 , PLA2G4E , RAPGEF2 , RASGRP2 , RPS6KA1 , TP53

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Histology: KIRC; Pathway: KEGG_P53_SIGNALING_PATHWAY; ; Total number of genes: 8

ATM , CCNB3 , CHEK2 , MDM2 , PTEN , THBS1 , TP53 , TSC2

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Histology: KIRC; Pathway: KEGG_TGF_BETA_SIGNALING_PATHWAY; ; Total number of genes: 1

THBS1

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Histology: KIRC; Pathway: REACTOME_PI3K_AKT_ACTIVATION; ; Total number of genes: 6

MDM2 , MTOR , NTRK1 , PIK3CA , PTEN , TSC2

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Histology: KIRC; Pathway: KEGG_MTOR_SIGNALING_PATHWAY; ; Total number of genes: 4

MTOR , PIK3CA , RPS6KA1 , TSC2

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Histology: KIRC; Pathway: KEGG_APOPTOSIS; ; Total number of genes: 5

ATM , NTRK1 , PIK3CA , TNFSF10 , TP53

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Histology: KIRC; Pathway: REACTOME_CELL_CYCLE; ; Total number of genes: 24

AKAP9 , ATM , BRCA1 , BTRC , CCNA1 , CENPJ , CEP131 , CHEK2 , DCTN1 , DCTN2 , DYNC1H1 , KIF20A , KNTC1 , MDM2 , MIS18BP1 , NUMA1 , PAFAH1B1 , POLE , RANBP2 , RPA1 , SMC3 , SYNE1 , SYNE2 , TP53

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Histology: KIRC; Pathway: REACTOME_DNA_REPAIR; ; Total number of genes: 10

ATM , BRCA1 , BRCA2 , DDB1 , FANCD2 , FANCE , POLE , PRKDC , REV3L , RPA1

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Histology: KIRC; Pathway: DRIVER_GENE; ; Total number of genes: 6

ATM , BAP1 , MTOR , PIK3CA , PTEN , TP53

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Histology: KIRC; Total number of genes: 81

AKAP9 , ARHGAP35 , ARHGAP5 , ATF4 , ATM , BAP1 , BRCA1 , BRCA2 , BTRC , CACNA1A , CACNA1C , CACNA1E , CACNA1G , CACNA1S , CCNA1 , CCNB3 , CENPJ , CEP131 , CHEK2 , COL11A1 , COL2A1 , COL5A2 , COL5A3 , COL6A3 , COL6A6 , DCTN1 , DCTN2 , DDB1 , DYNC1H1 , EGFR , FANCD2 , FANCE , FLNB , HSPA8 , IGF1R , IL1R2 , ITGA10 , ITGA11 , ITGAV , KIF20A , KNTC1 , LAMA5 , LAMB1 , LAMC1 , LAMC2 , LAMC3 , MAP3K1 , MAP3K5 , MAPK14 , MDM2 , MIS18BP1 , MTOR , MYLK , NF1 , NTRK1 , NUMA1 , PAFAH1B1 , PIK3CA , PLA2G4E , POLE , PRKDC , PTEN , RANBP2 , RAPGEF2 , RASGRP2 , RELN , REV3L , RPA1 , RPS6KA1 , SMC3 , SYNE1 , SYNE2 , THBS1 , TLN2 , TNC , TNFSF10 , TNN , TNR , TP53 , TSC2 , VWF

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Histology: LAML; Pathway: KEGG_MAPK_SIGNALING_PATHWAY; ; Total number of genes: 2

NRAS , TP53

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Histology: LAML; Pathway: KEGG_P53_SIGNALING_PATHWAY; ; Total number of genes: 1

TP53

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Histology: LAML; Pathway: KEGG_APOPTOSIS; ; Total number of genes: 1

TP53

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Histology: LAML; Pathway: REACTOME_CELL_CYCLE; ; Total number of genes: 5

RAD21 , SMC1A , SMC3 , STAG2 , TP53

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Histology: LAML; Pathway: DRIVER_GENE; ; Total number of genes: 7

FLT3 , IDH2 , KIT , PTPN11 , RUNX1 , TET2 , TP53

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Histology: LAML; Total number of genes: 12

FLT3 , IDH2 , KIT , NRAS , PTPN11 , RAD21 , RUNX1 , SMC1A , SMC3 , STAG2 , TET2 , TP53

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Histology: LGG; Pathway: KEGG_P53_SIGNALING_PATHWAY; ; Total number of genes: 2

PTEN , TP53

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Histology: LGG; Pathway: KEGG_FOCAL_ADHESION; ; Total number of genes: 4

EGFR , PIK3CA , PIK3R1 , PTEN

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Histology: LGG; Pathway: REACTOME_PI3K_AKT_ACTIVATION; ; Total number of genes: 3

PIK3CA , PIK3R1 , PTEN

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Histology: LGG; Pathway: KEGG_MAPK_SIGNALING_PATHWAY; ; Total number of genes: 3

EGFR , NF1 , TP53

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Histology: LGG; Pathway: KEGG_MTOR_SIGNALING_PATHWAY; ; Total number of genes: 2

PIK3CA , PIK3R1

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Histology: LGG; Pathway: KEGG_APOPTOSIS; ; Total number of genes: 3

PIK3CA , PIK3R1 , TP53

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Histology: LGG; Pathway: REACTOME_CELL_CYCLE; ; Total number of genes: 1

TP53

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Histology: LGG; Pathway: DRIVER_GENE; ; Total number of genes: 14

ARID1A , ATRX , CIC , EGFR , IDH1 , IDH2 , NF1 , NOTCH1 , PIK3CA , PIK3R1 , PTEN , PTPN11 , SMARCA4 , TP53

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Histology: LGG; Total number of genes: 14

ARID1A , ATRX , CIC , EGFR , IDH1 , IDH2 , NF1 , NOTCH1 , PIK3CA , PIK3R1 , PTEN , PTPN11 , SMARCA4 , TP53

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Histology: LIHC; Pathway: KEGG_FOCAL_ADHESION; ; Total number of genes: 47

ARHGAP35 , COL11A1 , COL11A2 , COL1A2 , COL2A1 , COL4A1 , COL4A2 , COL5A1 , COL5A3 , COL6A3 , COL6A6 , COMP , CTNNB1 , DIAPH1 , EGFR , FLNB , FLT1 , FN1 , HGF , IGF1R , ITGB4 , ITGB5 , LAMA1 , LAMA2 , LAMA3 , LAMA5 , LAMB2 , LAMB3 , LAMB4 , LAMC2 , PAK5 , PIK3CA , PRKCG , PTEN , PTK2 , RAPGEF1 , RELN , SOS1 , THBS1 , THBS3 , TLN1 , TLN2 , TNN , TNR , TNXB , VAV3 , VWF

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Histology: LIHC; Pathway: KEGG_ECM_RECEPTOR_INTERACTION; ; Total number of genes: 29

COL11A1 , COL11A2 , COL1A2 , COL2A1 , COL4A1 , COL4A2 , COL5A1 , COL5A3 , COL6A3 , COL6A6 , COMP , FN1 , ITGB4 , ITGB5 , LAMA1 , LAMA2 , LAMA3 , LAMA5 , LAMB2 , LAMB3 , LAMB4 , LAMC2 , RELN , THBS1 , THBS3 , TNN , TNR , TNXB , VWF

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Histology: LIHC; Pathway: KEGG_TGF_BETA_SIGNALING_PATHWAY; ; Total number of genes: 4

COMP , RBL2 , THBS1 , THBS3

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Histology: LIHC; Pathway: KEGG_MAPK_SIGNALING_PATHWAY; ; Total number of genes: 31

ATF4 , CACNA1B , CACNA1C , CACNA1E , CACNA1G , CACNA1H , CACNA1I , CACNA2D1 , CHUK , EGFR , FGFR4 , FLNB , IL1R1 , KRAS , MAP3K4 , NF1 , NFATC2 , NTRK1 , PLA2G4A , PRKCG , PTPN5 , RAPGEF2 , RASA1 , RPS6KA2 , RPS6KA3 , RPS6KA5 , RPS6KA6 , SOS1 , TAOK1 , TAOK2 , TP53

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Histology: LIHC; Pathway: KEGG_P53_SIGNALING_PATHWAY; ; Total number of genes: 9

APAF1 , ATM , ATR , CDKN1A , CDKN2A , PTEN , THBS1 , TP53 , TSC2

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Histology: LIHC; Pathway: REACTOME_PI3K_AKT_ACTIVATION; ; Total number of genes: 9

CDKN1A , CDKN1B , CHUK , MTOR , NTRK1 , PIK3CA , PTEN , RICTOR , TSC2

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Histology: LIHC; Pathway: KEGG_MTOR_SIGNALING_PATHWAY; ; Total number of genes: 10

MTOR , PIK3CA , RICTOR , RPS6KA2 , RPS6KA3 , RPS6KA6 , STRADA , TSC1 , TSC2 , ULK2

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Histology: LIHC; Pathway: KEGG_APOPTOSIS; ; Total number of genes: 8

APAF1 , ATM , CHUK , IL1R1 , IRAK1 , NTRK1 , PIK3CA , TP53

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Histology: LIHC; Pathway: REACTOME_CELL_CYCLE; ; Total number of genes: 37

AKAP9 , ALMS1 , ATM , ATR , BRCA1 , BTRC , CDC27 , CDKN1A , CDKN1B , CDKN2A , CEP135 , CEP192 , CEP250 , CEP290 , DIDO1 , DYNC1H1 , DYRK1A , HSP90AA1 , MCM10 , NDC80 , NUP133 , PSMD12 , PSME4 , RANBP2 , RB1 , RBL2 , SDCCAG8 , SGO2 , SMC1A , STAG1 , STAG2 , SYCP1 , SYCP2 , SYNE1 , SYNE2 , TAOK1 , TP53

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Histology: LIHC; Pathway: REACTOME_DNA_REPAIR; ; Total number of genes: 13

ATM , ATR , BRCA1 , BRCA2 , FANCA , FANCB , FANCM , POLR2A , POLR2B , PRKDC , RAD23B , REV1 , REV3L

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Histology: LIHC; Pathway: DRIVER_GENE; ; Total number of genes: 16

ACVR2A , ARID1A , AXIN1 , BAP1 , CDKN2A , CTNNB1 , IDH1 , IL6ST , KRAS , NSD2 , NUP133 , PIK3CA , RB1 , RPS6KA3 , TP53 , TSC2

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Histology: LIHC; Total number of genes: 134

ACVR2A , AKAP9 , ALMS1 , APAF1 , ARHGAP35 , ARID1A , ATF4 , ATM , ATR , AXIN1 , BAP1 , BRCA1 , BRCA2 , BTRC , CACNA1B , CACNA1C , CACNA1E , CACNA1G , CACNA1H , CACNA1I , CACNA2D1 , CDC27 , CDKN1A , CDKN1B , CDKN2A , CEP135 , CEP192 , CEP250 , CEP290 , CHUK , COL11A1 , COL11A2 , COL1A2 , COL2A1 , COL4A1 , COL4A2 , COL5A1 , COL5A3 , COL6A3 , COL6A6 , COMP , CTNNB1 , DIAPH1 , DIDO1 , DYNC1H1 , DYRK1A , EGFR , FANCA , FANCB , FANCM , FGFR4 , FLNB , FLT1 , FN1 , HGF , HSP90AA1 , IDH1 , IGF1R , IL1R1 , IL6ST , IRAK1 , ITGB4 , ITGB5 , KRAS , LAMA1 , LAMA2 , LAMA3 , LAMA5 , LAMB2 , LAMB3 , LAMB4 , LAMC2 , MAP3K4 , MCM10 , MTOR , NDC80 , NF1 , NFATC2 , NSD2 , NTRK1 , NUP133 , PAK5 , PIK3CA , PLA2G4A , POLR2A , POLR2B , PRKCG , PRKDC , PSMD12 , PSME4 , PTEN , PTK2 , PTPN5 , RAD23B , RANBP2 , RAPGEF1 , RAPGEF2 , RASA1 , RB1 , RBL2 , RELN , REV1 , REV3L , RICTOR , RPS6KA2 , RPS6KA3 , RPS6KA5 , RPS6KA6 , SDCCAG8 , SGO2 , SMC1A , SOS1 , STAG1 , STAG2 , STRADA , SYCP1 , SYCP2 , SYNE1 , SYNE2 , TAOK1 , TAOK2 , THBS1 , THBS3 , TLN1 , TLN2 , TNN , TNR , TNXB , TP53 , TSC1 , TSC2 , ULK2 , VAV3 , VWF

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Histology: LUAD; Pathway: KEGG_FOCAL_ADHESION; ; Total number of genes: 70

ACTN2 , AKT3 , ARHGAP35 , BRAF , COL11A1 , COL11A2 , COL1A2 , COL2A1 , COL3A1 , COL4A1 , COL4A2 , COL4A6 , COL5A1 , COL5A2 , COL5A3 , COL6A2 , COL6A3 , COL6A6 , CTNNB1 , DOCK1 , EGF , EGFR , ERBB2 , FLNC , FLT1 , FLT4 , GRB2 , HGF , ITGA1 , ITGA10 , ITGA2 , ITGA2B , ITGA4 , ITGA7 , ITGA8 , KDR , LAMA1 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , LAMB1 , LAMB2 , LAMB3 , LAMB4 , LAMC1 , LAMC3 , MET , MYLK , PAK5 , PDGFRA , PDGFRB , PIK3CA , PIK3CG , PIK3R5 , PRKCB , PRKCG , RELN , ROCK1 , SOS1 , SOS2 , THBS1 , THBS2 , TNC , TNN , TNR , TNXB , VAV3 , VEGFC , VWF

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Histology: LUAD; Pathway: KEGG_ECM_RECEPTOR_INTERACTION; ; Total number of genes: 40

COL11A1 , COL11A2 , COL1A2 , COL2A1 , COL3A1 , COL4A1 , COL4A2 , COL4A6 , COL5A1 , COL5A2 , COL5A3 , COL6A2 , COL6A3 , COL6A6 , ITGA1 , ITGA10 , ITGA2 , ITGA2B , ITGA4 , ITGA7 , ITGA8 , LAMA1 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , LAMB1 , LAMB2 , LAMB3 , LAMB4 , LAMC1 , LAMC3 , RELN , THBS1 , THBS2 , TNC , TNN , TNR , TNXB , VWF

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Histology: LUAD; Pathway: KEGG_TGF_BETA_SIGNALING_PATHWAY; ; Total number of genes: 4

PPP2R1A , ROCK1 , THBS1 , THBS2

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Histology: LUAD; Pathway: KEGG_MTOR_SIGNALING_PATHWAY; ; Total number of genes: 11

AKT3 , BRAF , MTOR , PIK3CA , PIK3CG , PIK3R5 , RICTOR , RPTOR , STK11 , ULK1 , VEGFC

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Histology: LUAD; Pathway: KEGG_APOPTOSIS; ; Total number of genes: 6

AKT3 , ATM , PIK3CA , PIK3CG , PIK3R5 , TP53

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Histology: LUAD; Pathway: KEGG_MAPK_SIGNALING_PATHWAY; ; Total number of genes: 36

AKT3 , BRAF , CACNA1A , CACNA1B , CACNA1C , CACNA1E , CACNA1G , CACNA1H , CACNA1S , CACNA2D1 , CACNA2D3 , CACNG3 , EGF , EGFR , FGFR2 , FLNC , GRB2 , HSPA1L , KRAS , MAP2K3 , MAP3K11 , MAP3K4 , NF1 , NTF3 , NTRK2 , PDGFRA , PDGFRB , PLA2G4A , PPM1B , PRKCB , PRKCG , PTPN5 , RAPGEF2 , SOS1 , SOS2 , TP53

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Histology: LUAD; Pathway: KEGG_P53_SIGNALING_PATHWAY; ; Total number of genes: 6

ATM , ATR , CCNB3 , CHEK1 , THBS1 , TP53

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Histology: LUAD; Pathway: REACTOME_PI3K_AKT_ACTIVATION; ; Total number of genes: 5

AKT3 , IRS1 , MTOR , PIK3CA , RICTOR

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Histology: LUAD; Pathway: REACTOME_CELL_CYCLE; ; Total number of genes: 36

AHCTF1 , AKAP9 , ALMS1 , ANAPC1 , ATM , ATR , BTRC , BUB1B , CCNA1 , CDC7 , CEP164 , CEP192 , CHEK1 , CKAP5 , DCTN1 , DIDO1 , DSN1 , DYNC1H1 , HIST1H2AC , HIST2H2AC , HSP90AA1 , KIF2B , KNTC1 , LIG1 , NUF2 , PCNT , POLE , PPP2R1A , PRIM2 , RANBP2 , RB1 , RUVBL1 , STAG2 , SYNE1 , SYNE2 , TP53

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Histology: LUAD; Pathway: REACTOME_DNA_REPAIR; ; Total number of genes: 10

ATM , ATR , BRCA2 , BRIP1 , FANCM , LIG1 , POLE , PRKDC , REV1 , TDP1

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Histology: LUAD; Pathway: DRIVER_GENE; ; Total number of genes: 14

ARID1A , ATM , BRAF , CTNNB1 , EGFR , KRAS , MET , MGA , NF1 , PIK3CA , RB1 , SMARCA4 , STK11 , TP53

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Histology: LUAD; Total number of genes: 145

ACTN2 , AHCTF1 , AKAP9 , AKT3 , ALMS1 , ANAPC1 , ARHGAP35 , ARID1A , ATM , ATR , BRAF , BRCA2 , BRIP1 , BTRC , BUB1B , CACNA1A , CACNA1B , CACNA1C , CACNA1E , CACNA1G , CACNA1H , CACNA1S , CACNA2D1 , CACNA2D3 , CACNG3 , CCNA1 , CCNB3 , CDC7 , CEP164 , CEP192 , CHEK1 , CKAP5 , COL11A1 , COL11A2 , COL1A2 , COL2A1 , COL3A1 , COL4A1 , COL4A2 , COL4A6 , COL5A1 , COL5A2 , COL5A3 , COL6A2 , COL6A3 , COL6A6 , CTNNB1 , DCTN1 , DIDO1 , DOCK1 , DSN1 , DYNC1H1 , EGF , EGFR , ERBB2 , FANCM , FGFR2 , FLNC , FLT1 , FLT4 , GRB2 , HGF , HIST1H2AC , HIST2H2AC , HSP90AA1 , HSPA1L , IRS1 , ITGA1 , ITGA10 , ITGA2 , ITGA2B , ITGA4 , ITGA7 , ITGA8 , KDR , KIF2B , KNTC1 , KRAS , LAMA1 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , LAMB1 , LAMB2 , LAMB3 , LAMB4 , LAMC1 , LAMC3 , LIG1 , MAP2K3 , MAP3K11 , MAP3K4 , MET , MGA , MTOR , MYLK , NF1 , NTF3 , NTRK2 , NUF2 , PAK5 , PCNT , PDGFRA , PDGFRB , PIK3CA , PIK3CG , PIK3R5 , PLA2G4A , POLE , PPM1B , PPP2R1A , PRIM2 , PRKCB , PRKCG , PRKDC , PTPN5 , RANBP2 , RAPGEF2 , RB1 , RELN , REV1 , RICTOR , ROCK1 , RPTOR , RUVBL1 , SMARCA4 , SOS1 , SOS2 , STAG2 , STK11 , SYNE1 , SYNE2 , TDP1 , THBS1 , THBS2 , TNC , TNN , TNR , TNXB , TP53 , ULK1 , VAV3 , VEGFC , VWF

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Histology: LUSC; Pathway: KEGG_FOCAL_ADHESION; ; Total number of genes: 52

ACTN2 , BRAF , COL11A1 , COL11A2 , COL1A1 , COL1A2 , COL2A1 , COL3A1 , COL4A1 , COL4A2 , COL4A4 , COL4A6 , COL5A1 , COL5A2 , COL5A3 , COL6A3 , COL6A6 , FLNA , FLNC , FLT1 , FN1 , HGF , ITGA10 , ITGA8 , ITGB1 , ITGB4 , KDR , LAMA1 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , MYLK , PAK5 , PDGFRA , PDGFRB , PIK3CA , PIK3CG , PRKCB , PRKCG , PTEN , RELN , SHC2 , SOS1 , SOS2 , THBS2 , TLN2 , TNC , TNN , TNR , TNXB , VWF

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Histology: LUSC; Pathway: KEGG_ECM_RECEPTOR_INTERACTION; ; Total number of genes: 32

COL11A1 , COL11A2 , COL1A1 , COL1A2 , COL2A1 , COL3A1 , COL4A1 , COL4A2 , COL4A4 , COL4A6 , COL5A1 , COL5A2 , COL5A3 , COL6A3 , COL6A6 , FN1 , ITGA10 , ITGA8 , ITGB1 , ITGB4 , LAMA1 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , RELN , THBS2 , TNC , TNN , TNR , TNXB , VWF

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Histology: LUSC; Pathway: KEGG_MAPK_SIGNALING_PATHWAY; ; Total number of genes: 27

BRAF , CACNA1A , CACNA1B , CACNA1C , CACNA1E , CACNA1F , CACNA1G , CACNA1I , CACNA2D1 , CACNA2D4 , FLNA , FLNC , MAPK8IP3 , MECOM , NF1 , PDGFRA , PDGFRB , PLA2G4A , PRKCB , PRKCG , PTPRR , RASA1 , RASGRP3 , SOS1 , SOS2 , TAOK1 , TP53

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Histology: LUSC; Pathway: KEGG_TGF_BETA_SIGNALING_PATHWAY; ; Total number of genes: 2

PPP2R1A , THBS2

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Histology: LUSC; Pathway: KEGG_P53_SIGNALING_PATHWAY; ; Total number of genes: 6

ATM , CCNB3 , CDKN2A , PTEN , TP53 , TSC2

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Histology: LUSC; Pathway: REACTOME_PI3K_AKT_ACTIVATION; ; Total number of genes: 3

PIK3CA , PTEN , TSC2

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Histology: LUSC; Pathway: KEGG_MTOR_SIGNALING_PATHWAY; ; Total number of genes: 4

BRAF , PIK3CA , PIK3CG , TSC2

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Histology: LUSC; Pathway: KEGG_APOPTOSIS; ; Total number of genes: 4

ATM , PIK3CA , PIK3CG , TP53

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Histology: LUSC; Pathway: REACTOME_CELL_CYCLE; ; Total number of genes: 34

AHCTF1 , AKAP9 , ALMS1 , ATM , CDKN2A , CENPP , CEP135 , CEP164 , CEP192 , CEP290 , CEP63 , DIDO1 , DYNC1H1 , KIF2B , LIG1 , MCM5 , NINL , NUP133 , PCNT , POT1 , PPP2R1A , PRIM2 , PSMC2 , RANBP2 , RANGAP1 , RB1 , SGO2 , SMC1B , STAG2 , SYNE1 , SYNE2 , TAOK1 , TP53 , TUBGCP5

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Histology: LUSC; Pathway: REACTOME_DNA_REPAIR; ; Total number of genes: 6

ATM , BRCA2 , FANCM , LIG1 , LIG4 , PRKDC

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Histology: LUSC; Pathway: DRIVER_GENE; ; Total number of genes: 7

CDKN2A , NF1 , PIK3CA , PTEN , RASA1 , RB1 , TP53

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Histology: LUSC; Total number of genes: 108

ACTN2 , AHCTF1 , AKAP9 , ALMS1 , ATM , BRAF , BRCA2 , CACNA1A , CACNA1B , CACNA1C , CACNA1E , CACNA1F , CACNA1G , CACNA1I , CACNA2D1 , CACNA2D4 , CCNB3 , CDKN2A , CENPP , CEP135 , CEP164 , CEP192 , CEP290 , CEP63 , COL11A1 , COL11A2 , COL1A1 , COL1A2 , COL2A1 , COL3A1 , COL4A1 , COL4A2 , COL4A4 , COL4A6 , COL5A1 , COL5A2 , COL5A3 , COL6A3 , COL6A6 , DIDO1 , DYNC1H1 , FANCM , FLNA , FLNC , FLT1 , FN1 , HGF , ITGA10 , ITGA8 , ITGB1 , ITGB4 , KDR , KIF2B , LAMA1 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , LIG1 , LIG4 , MAPK8IP3 , MCM5 , MECOM , MYLK , NF1 , NINL , NUP133 , PAK5 , PCNT , PDGFRA , PDGFRB , PIK3CA , PIK3CG , PLA2G4A , POT1 , PPP2R1A , PRIM2 , PRKCB , PRKCG , PRKDC , PSMC2 , PTEN , PTPRR , RANBP2 , RANGAP1 , RASA1 , RASGRP3 , RB1 , RELN , SGO2 , SHC2 , SMC1B , SOS1 , SOS2 , STAG2 , SYNE1 , SYNE2 , TAOK1 , THBS2 , TLN2 , TNC , TNN , TNR , TNXB , TP53 , TSC2 , TUBGCP5 , VWF

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Histology: OV; Pathway: KEGG_FOCAL_ADHESION; ; Total number of genes: 8

COL5A3 , COL6A3 , LAMA2 , LAMB4 , MYLK , RELN , TNXB , VAV2

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Histology: OV; Pathway: KEGG_ECM_RECEPTOR_INTERACTION; ; Total number of genes: 6

COL5A3 , COL6A3 , LAMA2 , LAMB4 , RELN , TNXB

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Histology: OV; Pathway: KEGG_MAPK_SIGNALING_PATHWAY; ; Total number of genes: 3

CACNA1C , NF1 , TP53

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Histology: OV; Pathway: KEGG_P53_SIGNALING_PATHWAY; ; Total number of genes: 1

TP53

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Histology: OV; Pathway: KEGG_APOPTOSIS; ; Total number of genes: 1

TP53

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Histology: OV; Pathway: REACTOME_CELL_CYCLE; ; Total number of genes: 3

RB1 , SYNE1 , TP53

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Histology: OV; Pathway: REACTOME_DNA_REPAIR; ; Total number of genes: 2

BRCA2 , PRKDC

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Histology: OV; Pathway: DRIVER_GENE; ; Total number of genes: 4

CDK12 , NF1 , RB1 , TP53

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Histology: OV; Total number of genes: 16

BRCA2 , CACNA1C , CDK12 , COL5A3 , COL6A3 , LAMA2 , LAMB4 , MYLK , NF1 , PRKDC , RB1 , RELN , SYNE1 , TNXB , TP53 , VAV2

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Histology: PAAD; Pathway: KEGG_FOCAL_ADHESION; ; Total number of genes: 6

COL11A1 , FLNA , FLNC , FLT4 , RELN , TNC

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Histology: PAAD; Pathway: KEGG_ECM_RECEPTOR_INTERACTION; ; Total number of genes: 3

COL11A1 , RELN , TNC

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Histology: PAAD; Pathway: KEGG_MAPK_SIGNALING_PATHWAY; ; Total number of genes: 9

CACNA1B , FLNA , FLNC , KRAS , NGF , RPS6KA6 , TGFBR1 , TGFBR2 , TP53

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Histology: PAAD; Pathway: KEGG_APOPTOSIS; ; Total number of genes: 2

NGF , TP53

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Histology: PAAD; Pathway: REACTOME_PI3K_AKT_ACTIVATION; ; Total number of genes: 1

NGF

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Histology: PAAD; Pathway: KEGG_MTOR_SIGNALING_PATHWAY; ; Total number of genes: 1

RPS6KA6

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Histology: PAAD; Pathway: KEGG_P53_SIGNALING_PATHWAY; ; Total number of genes: 2

CDKN2A , TP53

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Histology: PAAD; Pathway: REACTOME_CELL_CYCLE; ; Total number of genes: 3

CDKN2A , SYNE1 , TP53

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Histology: PAAD; Pathway: KEGG_TGF_BETA_SIGNALING_PATHWAY; ; Total number of genes: 2

TGFBR1 , TGFBR2

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Histology: PAAD; Pathway: DRIVER_GENE; ; Total number of genes: 8

ARID1A , CDKN2A , GNAS , KDM6A , KRAS , SMAD4 , TGFBR2 , TP53

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Histology: PAAD; Total number of genes: 19

ARID1A , CACNA1B , CDKN2A , COL11A1 , FLNA , FLNC , FLT4 , GNAS , KDM6A , KRAS , NGF , RELN , RPS6KA6 , SMAD4 , SYNE1 , TGFBR1 , TGFBR2 , TNC , TP53

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Histology: PRAD; Pathway: KEGG_TGF_BETA_SIGNALING_PATHWAY; ; Total number of genes: 1

ROCK1

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Histology: PRAD; Pathway: KEGG_FOCAL_ADHESION; ; Total number of genes: 13

COL11A1 , COL5A1 , COL5A3 , COL6A3 , CTNNB1 , FLT1 , KDR , LAMA1 , PIK3CA , PIK3CG , PTEN , ROCK1 , TNXB

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Histology: PRAD; Pathway: KEGG_ECM_RECEPTOR_INTERACTION; ; Total number of genes: 6

COL11A1 , COL5A1 , COL5A3 , COL6A3 , LAMA1 , TNXB

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Histology: PRAD; Pathway: KEGG_P53_SIGNALING_PATHWAY; ; Total number of genes: 4

ATM , CHEK2 , PTEN , TP53

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Histology: PRAD; Pathway: REACTOME_PI3K_AKT_ACTIVATION; ; Total number of genes: 4

CDKN1B , NTRK1 , PIK3CA , PTEN

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Histology: PRAD; Pathway: KEGG_MTOR_SIGNALING_PATHWAY; ; Total number of genes: 2

PIK3CA , PIK3CG

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Histology: PRAD; Pathway: KEGG_APOPTOSIS; ; Total number of genes: 5

ATM , NTRK1 , PIK3CA , PIK3CG , TP53

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Histology: PRAD; Pathway: REACTOME_CELL_CYCLE; ; Total number of genes: 10

AKAP9 , ATM , CDC27 , CDKN1B , CHEK2 , DIDO1 , DYNC1H1 , MCM6 , SYNE1 , TP53

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Histology: PRAD; Pathway: KEGG_MAPK_SIGNALING_PATHWAY; ; Total number of genes: 5

CACNA1A , CACNA1E , MECOM , NTRK1 , TP53

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Histology: PRAD; Pathway: REACTOME_DNA_REPAIR; ; Total number of genes: 3

ATM , PRKDC , XRCC6

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Histology: PRAD; Pathway: DRIVER_GENE; ; Total number of genes: 6

APC , CTNNB1 , IDH1 , PIK3CA , PTEN , TP53

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Histology: PRAD; Total number of genes: 31

AKAP9 , APC , ATM , CACNA1A , CACNA1E , CDC27 , CDKN1B , CHEK2 , COL11A1 , COL5A1 , COL5A3 , COL6A3 , CTNNB1 , DIDO1 , DYNC1H1 , FLT1 , IDH1 , KDR , LAMA1 , MCM6 , MECOM , NTRK1 , PIK3CA , PIK3CG , PRKDC , PTEN , ROCK1 , SYNE1 , TNXB , TP53 , XRCC6

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Histology: SKCM; Pathway: KEGG_FOCAL_ADHESION; ; Total number of genes: 135

ACTB , ACTG1 , ACTN2 , ACTN3 , ACTN4 , AKT2 , ARHGAP35 , ARHGAP5 , BAD , BCAR1 , BIRC2 , BIRC3 , BRAF , CCND2 , COL11A1 , COL11A2 , COL1A1 , COL1A2 , COL2A1 , COL3A1 , COL4A1 , COL4A2 , COL4A4 , COL4A6 , COL5A1 , COL5A2 , COL5A3 , COL6A1 , COL6A2 , COL6A3 , COL6A6 , CTNNB1 , DIAPH1 , DOCK1 , EGF , EGFR , ERBB2 , FLNA , FLNB , FLNC , FLT1 , FLT4 , FN1 , FYN , HGF , IBSP , IGF1 , IGF1R , ITGA1 , ITGA10 , ITGA11 , ITGA2 , ITGA2B , ITGA4 , ITGA5 , ITGA6 , ITGA7 , ITGA8 , ITGA9 , ITGAV , ITGB3 , ITGB4 , ITGB6 , ITGB8 , KDR , LAMA1 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , LAMB1 , LAMB2 , LAMB3 , LAMB4 , LAMC1 , LAMC2 , LAMC3 , MAP2K1 , MAPK10 , MET , MYL2 , MYLK , MYLK2 , MYLK3 , PAK3 , PAK5 , PAK6 , PARVA , PDGFC , PDGFD , PDGFRA , PDGFRB , PIK3CA , PIK3CB , PIK3CD , PIK3CG , PIK3R1 , PIK3R5 , PRKCA , PRKCB , PRKCG , PTEN , RAC1 , RAF1 , RAPGEF1 , RASGRF1 , RELN , ROCK1 , ROCK2 , SHC1 , SHC2 , SHC3 , SOS1 , SOS2 , SPP1 , THBS1 , THBS2 , THBS3 , THBS4 , TLN1 , TLN2 , TNC , TNN , TNR , TNXB , VAV1 , VAV2 , VAV3 , VCL , VEGFA , VEGFC , VEGFD , VTN , VWF , ZYX

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Histology: SKCM; Pathway: KEGG_ECM_RECEPTOR_INTERACTION; ; Total number of genes: 59

COL11A1 , COL11A2 , COL1A1 , COL1A2 , COL2A1 , COL3A1 , COL4A1 , COL4A2 , COL4A4 , COL4A6 , COL5A1 , COL5A2 , COL5A3 , COL6A1 , COL6A2 , COL6A3 , COL6A6 , FN1 , IBSP , ITGA1 , ITGA10 , ITGA11 , ITGA2 , ITGA2B , ITGA4 , ITGA5 , ITGA6 , ITGA7 , ITGA8 , ITGA9 , ITGAV , ITGB3 , ITGB4 , ITGB6 , ITGB8 , LAMA1 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , LAMB1 , LAMB2 , LAMB3 , LAMB4 , LAMC1 , LAMC2 , LAMC3 , RELN , SPP1 , THBS1 , THBS2 , THBS3 , THBS4 , TNC , TNN , TNR , TNXB , VTN , VWF

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Histology: SKCM; Pathway: KEGG_P53_SIGNALING_PATHWAY; ; Total number of genes: 22

ADGRB1 , ATM , ATR , BAX , CASP8 , CCNB3 , CCND2 , CDK4 , CDKN2A , CHEK2 , COP1 , FAS , IGF1 , PIDD1 , PTEN , SERPINB5 , SESN2 , STEAP3 , THBS1 , TNFRSF10B , TP53 , TSC2

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Histology: SKCM; Pathway: KEGG_MTOR_SIGNALING_PATHWAY; ; Total number of genes: 22

AKT2 , BRAF , EIF4B , IGF1 , MTOR , PIK3CA , PIK3CB , PIK3CD , PIK3CG , PIK3R1 , PIK3R5 , PRKAA2 , RICTOR , RPS6KA1 , RPS6KA6 , RPTOR , TSC1 , TSC2 , ULK1 , VEGFA , VEGFC , VEGFD

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Histology: SKCM; Pathway: KEGG_APOPTOSIS; ; Total number of genes: 35

AKT2 , ATM , BAD , BAX , BIRC2 , BIRC3 , CASP10 , CASP7 , CASP8 , CHP2 , CSF2RB , ENDOD1 , FAS , FASLG , IL1A , IL1B , IL1R1 , IRAK2 , IRAK3 , MAP3K14 , NGF , NTRK1 , PIK3CA , PIK3CB , PIK3CD , PIK3CG , PIK3R1 , PIK3R5 , PPP3CA , PPP3R2 , PRKACG , PRKAR1B , TNFRSF10B , TNFRSF10D , TP53

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Histology: SKCM; Pathway: KEGG_TGF_BETA_SIGNALING_PATHWAY; ; Total number of genes: 9

MYC , RBL1 , ROCK1 , ROCK2 , TGFBR2 , THBS1 , THBS2 , THBS3 , THBS4

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Histology: SKCM; Pathway: KEGG_MAPK_SIGNALING_PATHWAY; ; Total number of genes: 126

AKT2 , ATF2 , ATF4 , BDNF , BRAF , CACNA1A , CACNA1B , CACNA1C , CACNA1D , CACNA1E , CACNA1F , CACNA1G , CACNA1H , CACNA1I , CACNA1S , CACNA2D1 , CACNA2D2 , CACNA2D3 , CACNA2D4 , CACNB2 , CACNB4 , CACNG3 , CACNG5 , CACNG7 , CDC25B , CHP2 , DUSP10 , EGF , EGFR , FAS , FASLG , FGF10 , FGF12 , FGF13 , FGF23 , FGF5 , FGF7 , FGFR1 , FGFR2 , FGFR3 , FGFR4 , FLNA , FLNB , FLNC , GNA12 , HSPA1L , HSPA6 , HSPA8 , IL1A , IL1B , IL1R1 , MAP2K1 , MAP2K2 , MAP2K3 , MAP2K4 , MAP2K5 , MAP2K7 , MAP3K1 , MAP3K11 , MAP3K13 , MAP3K14 , MAP3K2 , MAP3K4 , MAP3K5 , MAP3K6 , MAP4K1 , MAP4K2 , MAP4K3 , MAP4K4 , MAPK10 , MAPK13 , MAPK8IP2 , MAPK8IP3 , MAPKAPK2 , MAPKAPK3 , MAPT , MECOM , MKNK2 , MYC , NF1 , NFATC2 , NFATC4 , NGF , NLK , NRAS , NTRK1 , NTRK2 , PDGFRA , PDGFRB , PLA2G3 , PLA2G4A , PLA2G4E , PLA2G6 , PPM1A , PPP3CA , PPP3R2 , PRKACG , PRKCA , PRKCB , PRKCG , PTPN5 , PTPN7 , PTPRR , RAC1 , RAF1 , RAPGEF2 , RASA2 , RASGRF1 , RASGRF2 , RASGRP1 , RASGRP2 , RASGRP3 , RASGRP4 , RELB , RPS6KA1 , RPS6KA4 , RPS6KA5 , RPS6KA6 , SOS1 , SOS2 , TAB1 , TAB2 , TAOK1 , TAOK2 , TGFBR2 , TP53

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Histology: SKCM; Pathway: REACTOME_PI3K_AKT_ACTIVATION; ; Total number of genes: 13

AKT2 , BAD , FOXO1 , MTOR , NGF , NTRK1 , PHLPP1 , PIK3CA , PIK3CB , PIK3R1 , PTEN , RICTOR , TSC2

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Histology: SKCM; Pathway: REACTOME_CELL_CYCLE; ; Total number of genes: 94

ACD , AHCTF1 , AKAP9 , ALMS1 , ANAPC1 , ANAPC2 , ATM , ATR , BRCA1 , BUB1 , BUB1B , CCND2 , CDC25B , CDK4 , CDK5RAP2 , CDKN2A , CENPJ , CEP131 , CEP164 , CEP192 , CEP250 , CEP290 , CEP63 , CEP72 , CEP76 , CHEK2 , CLASP1 , CLIP1 , CNTRL , COP1 , DCTN1 , DIDO1 , DNA2 , DYNC1H1 , E2F1 , ERCC6L , HJURP , INCENP , KIF2A , KNL1 , LIG1 , MCM10 , MCM2 , MCM3 , MCM4 , MIS18BP1 , MYBL2 , MYC , NEDD1 , NEK2 , NINL , NUMA1 , NUP107 , ORC1 , PAFAH1B1 , PCM1 , PCNT , PLK4 , POLA2 , POLD1 , POLE , POT1 , PPP2R2A , PPP2R5C , PSMA4 , PSMA8 , PSME4 , RAD21 , RAD9A , RANBP2 , RB1 , RBL1 , RSF1 , RUVBL2 , SDCCAG8 , SGO2 , SKA1 , SMC1B , SPC25 , STAG1 , STAG2 , STAG3 , SYCP1 , SYCP2 , SYNE1 , SYNE2 , TAOK1 , TERT , TP53 , TUBB4A , TUBGCP2 , TUBGCP3 , TUBGCP5 , WRAP53

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Histology: SKCM; Pathway: REACTOME_DNA_REPAIR; ; Total number of genes: 6

ATM , ATR , BRCA1 , LIG1 , POLD1 , POLE

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Histology: SKCM; Pathway: DRIVER_GENE; ; Total number of genes: 14

BRAF , CDKN2A , CTNNB1 , DACH1 , IDH1 , KIT , MAP2K1 , MECOM , NF1 , NRAS , PTEN , RAC1 , RB1 , TP53

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Histology: SKCM; Total number of genes: 361

ACD , ACTB , ACTG1 , ACTN2 , ACTN3 , ACTN4 , ADGRB1 , AHCTF1 , AKAP9 , AKT2 , ALMS1 , ANAPC1 , ANAPC2 , ARHGAP35 , ARHGAP5 , ATF2 , ATF4 , ATM , ATR , BAD , BAX , BCAR1 , BDNF , BIRC2 , BIRC3 , BRAF , BRCA1 , BUB1 , BUB1B , CACNA1A , CACNA1B , CACNA1C , CACNA1D , CACNA1E , CACNA1F , CACNA1G , CACNA1H , CACNA1I , CACNA1S , CACNA2D1 , CACNA2D2 , CACNA2D3 , CACNA2D4 , CACNB2 , CACNB4 , CACNG3 , CACNG5 , CACNG7 , CASP10 , CASP7 , CASP8 , CCNB3 , CCND2 , CDC25B , CDK4 , CDK5RAP2 , CDKN2A , CENPJ , CEP131 , CEP164 , CEP192 , CEP250 , CEP290 , CEP63 , CEP72 , CEP76 , CHEK2 , CHP2 , CLASP1 , CLIP1 , CNTRL , COL11A1 , COL11A2 , COL1A1 , COL1A2 , COL2A1 , COL3A1 , COL4A1 , COL4A2 , COL4A4 , COL4A6 , COL5A1 , COL5A2 , COL5A3 , COL6A1 , COL6A2 , COL6A3 , COL6A6 , COP1 , CSF2RB , CTNNB1 , DACH1 , DCTN1 , DIAPH1 , DIDO1 , DNA2 , DOCK1 , DUSP10 , DYNC1H1 , E2F1 , EGF , EGFR , EIF4B , ENDOD1 , ERBB2 , ERCC6L , FAS , FASLG , FGF10 , FGF12 , FGF13 , FGF23 , FGF5 , FGF7 , FGFR1 , FGFR2 , FGFR3 , FGFR4 , FLNA , FLNB , FLNC , FLT1 , FLT4 , FN1 , FOXO1 , FYN , GNA12 , HGF , HJURP , HSPA1L , HSPA6 , HSPA8 , IBSP , IDH1 , IGF1 , IGF1R , IL1A , IL1B , IL1R1 , INCENP , IRAK2 , IRAK3 , ITGA1 , ITGA10 , ITGA11 , ITGA2 , ITGA2B , ITGA4 , ITGA5 , ITGA6 , ITGA7 , ITGA8 , ITGA9 , ITGAV , ITGB3 , ITGB4 , ITGB6 , ITGB8 , KDR , KIF2A , KIT , KNL1 , LAMA1 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , LAMB1 , LAMB2 , LAMB3 , LAMB4 , LAMC1 , LAMC2 , LAMC3 , LIG1 , MAP2K1 , MAP2K2 , MAP2K3 , MAP2K4 , MAP2K5 , MAP2K7 , MAP3K1 , MAP3K11 , MAP3K13 , MAP3K14 , MAP3K2 , MAP3K4 , MAP3K5 , MAP3K6 , MAP4K1 , MAP4K2 , MAP4K3 , MAP4K4 , MAPK10 , MAPK13 , MAPK8IP2 , MAPK8IP3 , MAPKAPK2 , MAPKAPK3 , MAPT , MCM10 , MCM2 , MCM3 , MCM4 , MECOM , MET , MIS18BP1 , MKNK2 , MTOR , MYBL2 , MYC , MYL2 , MYLK , MYLK2 , MYLK3 , NEDD1 , NEK2 , NF1 , NFATC2 , NFATC4 , NGF , NINL , NLK , NRAS , NTRK1 , NTRK2 , NUMA1 , NUP107 , ORC1 , PAFAH1B1 , PAK3 , PAK5 , PAK6 , PARVA , PCM1 , PCNT , PDGFC , PDGFD , PDGFRA , PDGFRB , PHLPP1 , PIDD1 , PIK3CA , PIK3CB , PIK3CD , PIK3CG , PIK3R1 , PIK3R5 , PLA2G3 , PLA2G4A , PLA2G4E , PLA2G6 , PLK4 , POLA2 , POLD1 , POLE , POT1 , PPM1A , PPP2R2A , PPP2R5C , PPP3CA , PPP3R2 , PRKAA2 , PRKACG , PRKAR1B , PRKCA , PRKCB , PRKCG , PSMA4 , PSMA8 , PSME4 , PTEN , PTPN5 , PTPN7 , PTPRR , RAC1 , RAD21 , RAD9A , RAF1 , RANBP2 , RAPGEF1 , RAPGEF2 , RASA2 , RASGRF1 , RASGRF2 , RASGRP1 , RASGRP2 , RASGRP3 , RASGRP4 , RB1 , RBL1 , RELB , RELN , RICTOR , ROCK1 , ROCK2 , RPS6KA1 , RPS6KA4 , RPS6KA5 , RPS6KA6 , RPTOR , RSF1 , RUVBL2 , SDCCAG8 , SERPINB5 , SESN2 , SGO2 , SHC1 , SHC2 , SHC3 , SKA1 , SMC1B , SOS1 , SOS2 , SPC25 , SPP1 , STAG1 , STAG2 , STAG3 , STEAP3 , SYCP1 , SYCP2 , SYNE1 , SYNE2 , TAB1 , TAB2 , TAOK1 , TAOK2 , TERT , TGFBR2 , THBS1 , THBS2 , THBS3 , THBS4 , TLN1 , TLN2 , TNC , TNFRSF10B , TNFRSF10D , TNN , TNR , TNXB , TP53 , TSC1 , TSC2 , TUBB4A , TUBGCP2 , TUBGCP3 , TUBGCP5 , ULK1 , VAV1 , VAV2 , VAV3 , VCL , VEGFA , VEGFC , VEGFD , VTN , VWF , WRAP53 , ZYX

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Histology: THCA; Pathway: KEGG_MAPK_SIGNALING_PATHWAY; ; Total number of genes: 4

BRAF , CACNA1E , HRAS , NRAS

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Histology: THCA; Pathway: KEGG_FOCAL_ADHESION; ; Total number of genes: 2

BRAF , HRAS

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Histology: THCA; Pathway: KEGG_MTOR_SIGNALING_PATHWAY; ; Total number of genes: 1

BRAF

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Histology: THCA; Pathway: KEGG_P53_SIGNALING_PATHWAY; ; Total number of genes: 1

PPM1D

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Histology: THCA; Pathway: DRIVER_GENE; ; Total number of genes: 3

BRAF , HRAS , NRAS

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Histology: THCA; Total number of genes: 5

BRAF , CACNA1E , HRAS , NRAS , PPM1D

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Histology: UCEC; Pathway: KEGG_FOCAL_ADHESION; ; Total number of genes: 107

ACTG1 , ACTN1 , ACTN2 , ARHGAP35 , ARHGAP5 , BCAR1 , BRAF , CAPN2 , CCND1 , COL11A1 , COL1A1 , COL1A2 , COL2A1 , COL3A1 , COL4A1 , COL4A2 , COL4A4 , COL4A6 , COL5A1 , COL5A2 , COL5A3 , COL6A2 , COL6A3 , COL6A6 , CRKL , CTNNB1 , DIAPH1 , DOCK1 , EGF , ERBB2 , FLNA , FLNB , FLNC , FLT1 , FN1 , HGF , IBSP , IGF1 , IGF1R , ITGA1 , ITGA10 , ITGA2 , ITGA2B , ITGA3 , ITGA5 , ITGA7 , ITGA8 , ITGA9 , ITGAV , ITGB3 , ITGB4 , ITGB5 , ITGB6 , KDR , LAMA1 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , LAMB1 , LAMB2 , LAMB3 , LAMB4 , LAMC1 , LAMC2 , LAMC3 , MAPK10 , MAPK8 , MET , MYL7 , MYLK , MYLK3 , PAK3 , PAK5 , PDGFRA , PDGFRB , PIK3CA , PIK3CB , PIK3CD , PIK3CG , PIK3R1 , PIK3R3 , PIP5K1C , PPP1R12A , PRKCA , PTEN , PTK2 , RAPGEF1 , RASGRF1 , RELN , ROCK1 , ROCK2 , SOS1 , SOS2 , THBS1 , THBS2 , THBS4 , TLN1 , TLN2 , TNC , TNN , TNR , TNXB , VAV3 , VTN , VWF , XIAP

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Histology: UCEC; Pathway: KEGG_ECM_RECEPTOR_INTERACTION; ; Total number of genes: 53

COL11A1 , COL1A1 , COL1A2 , COL2A1 , COL3A1 , COL4A1 , COL4A2 , COL4A4 , COL4A6 , COL5A1 , COL5A2 , COL5A3 , COL6A2 , COL6A3 , COL6A6 , FN1 , IBSP , ITGA1 , ITGA10 , ITGA2 , ITGA2B , ITGA3 , ITGA5 , ITGA7 , ITGA8 , ITGA9 , ITGAV , ITGB3 , ITGB4 , ITGB5 , ITGB6 , LAMA1 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , LAMB1 , LAMB2 , LAMB3 , LAMB4 , LAMC1 , LAMC2 , LAMC3 , RELN , THBS1 , THBS2 , THBS4 , TNC , TNN , TNR , TNXB , VTN , VWF

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Histology: UCEC; Pathway: KEGG_P53_SIGNALING_PATHWAY; ; Total number of genes: 19

ADGRB1 , APAF1 , ATM , ATR , CASP8 , CCNB1 , CCNB3 , CCND1 , CCNE2 , CHEK2 , FAS , IGF1 , PPM1D , PTEN , RRM2 , SESN3 , STEAP3 , THBS1 , TP53

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Histology: UCEC; Pathway: KEGG_MTOR_SIGNALING_PATHWAY; ; Total number of genes: 20

BRAF , CAB39L , EIF4B , HIF1A , IGF1 , MTOR , PIK3CA , PIK3CB , PIK3CD , PIK3CG , PIK3R1 , PIK3R3 , PRKAA2 , RICTOR , RPS6KA2 , RPS6KA3 , RPS6KA6 , RPTOR , TSC1 , ULK2

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Histology: UCEC; Pathway: KEGG_APOPTOSIS; ; Total number of genes: 26

AIFM1 , APAF1 , ATM , CAPN2 , CASP10 , CASP6 , CASP8 , FAS , FASLG , IKBKB , IL1RAP , IRAK3 , IRAK4 , MAP3K14 , NFKB1 , NTRK1 , PIK3CA , PIK3CB , PIK3CD , PIK3CG , PIK3R1 , PIK3R3 , PRKACG , RIPK1 , TP53 , XIAP

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Histology: UCEC; Pathway: KEGG_TGF_BETA_SIGNALING_PATHWAY; ; Total number of genes: 12

CUL1 , MYC , PPP2R1A , RBL1 , RBL2 , ROCK1 , ROCK2 , TFDP1 , TGFBR1 , THBS1 , THBS2 , THBS4

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Histology: UCEC; Pathway: KEGG_MAPK_SIGNALING_PATHWAY; ; Total number of genes: 92

BDNF , BRAF , CACNA1A , CACNA1B , CACNA1C , CACNA1D , CACNA1E , CACNA1F , CACNA1G , CACNA1I , CACNA1S , CACNA2D1 , CACNA2D2 , CACNA2D3 , CACNA2D4 , CACNB1 , CACNB4 , CACNG3 , CACNG7 , CRKL , DUSP10 , EGF , FAS , FASLG , FGF5 , FGFR2 , FLNA , FLNB , FLNC , HSPA6 , HSPA8 , IKBKB , KRAS , MAP2K4 , MAP2K6 , MAP3K1 , MAP3K13 , MAP3K14 , MAP3K2 , MAP3K4 , MAP3K5 , MAP3K8 , MAP4K1 , MAP4K3 , MAP4K4 , MAPK10 , MAPK7 , MAPK8 , MAPKAPK2 , MAPKAPK5 , MAPT , MAX , MECOM , MEF2C , MYC , NF1 , NFATC2 , NFKB1 , NFKB2 , NRAS , NTRK1 , NTRK2 , PDGFRA , PDGFRB , PLA2G2E , PLA2G4A , PLA2G6 , PPP5C , PRKACG , PRKCA , PTPN5 , PTPRR , RAPGEF2 , RASA1 , RASA2 , RASGRF1 , RASGRF2 , RASGRP3 , RPS6KA2 , RPS6KA3 , RPS6KA6 , SOS1 , SOS2 , STK3 , STK4 , STMN1 , TAB2 , TAOK1 , TAOK2 , TGFBR1 , TP53 , TRAF6

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Histology: UCEC; Pathway: REACTOME_PI3K_AKT_ACTIVATION; ; Total number of genes: 13

CREB1 , FOXO1 , FOXO4 , GSK3A , IRS1 , MTOR , NTRK1 , PHLPP1 , PIK3CA , PIK3CB , PIK3R1 , PTEN , RICTOR

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Histology: UCEC; Pathway: REACTOME_CELL_CYCLE; ; Total number of genes: 134

AHCTF1 , AKAP9 , ALMS1 , ANAPC1 , ATM , ATR , BRCA1 , BTRC , BUB1B , CCNA2 , CCNB1 , CCND1 , CCNE2 , CDC14A , CDC16 , CDC23 , CDC27 , CDC45 , CDC7 , CDK5RAP2 , CENPI , CENPJ , CEP135 , CEP164 , CEP192 , CEP250 , CEP290 , CEP72 , CEP76 , CETN2 , CHEK2 , CKAP5 , CLASP1 , CLIP1 , CNTRL , CUL1 , DCTN1 , DIDO1 , DKC1 , DNA2 , DYNC1H1 , DYRK1A , ERCC6L , FBXO5 , GORASP1 , HIST1H2BD , HIST1H2BL , KIF18A , KIF23 , KIF2B , KIF2C , KNL1 , KNTC1 , LIG1 , LIN54 , LIN9 , LMNA , MAX , MCM2 , MCM4 , MCM5 , MCM6 , MCM7 , MIS18BP1 , MYBL2 , MYC , NDC80 , NINL , NUF2 , NUMA1 , NUP107 , NUP133 , NUP85 , OFD1 , ORC1 , ORC5 , PCM1 , PCNT , PLK4 , POLA1 , POLD1 , POLE , POT1 , PPP2R1A , PPP2R5A , PPP2R5E , PSMB10 , PSMC6 , PSMD1 , PSMD10 , PSMD3 , PSMD5 , PSME4 , RAD1 , RAD17 , RAD21 , RANBP2 , RB1 , RBBP7 , RBL1 , RBL2 , RCC2 , RFC5 , RPA1 , RRM2 , RSF1 , SDCCAG8 , SEH1L , SGO1 , SGO2 , SKP2 , SMARCA5 , SMC1A , SMC1B , STAG1 , STAG2 , STAG3 , SUN2 , SYCP1 , SYCP2 , SYNE1 , SYNE2 , TAOK1 , TFDP1 , TP53 , TUBA1A , TUBA4A , TUBG1 , TUBG2 , TUBGCP2 , TUBGCP3 , TUBGCP5 , TUBGCP6 , XPO1

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Histology: UCEC; Pathway: REACTOME_DNA_REPAIR; ; Total number of genes: 37

ATM , ATR , BRCA1 , BRCA2 , BRIP1 , DDB1 , ERCC3 , ERCC4 , ERCC5 , ERCC6 , FANCA , FANCB , FANCD2 , FANCE , FANCG , FANCM , GTF2H1 , LIG1 , LIG3 , LIG4 , MBD4 , MDC1 , NBN , POLD1 , POLE , POLR2A , POLR2B , PRKDC , RAD50 , REV1 , REV3L , RFC5 , RPA1 , TP53BP1 , XAB2 , XRCC5 , XRCC6

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Histology: UCEC; Pathway: DRIVER_GENE; ; Total number of genes: 25

ACVR1 , ARID1A , ATM , ATR , CCND1 , CTNNB1 , DICER1 , EP300 , ERBB2 , ERBB3 , FBXW7 , FGFR2 , KRAS , MAP3K1 , MSH6 , NRAS , PIK3CA , PIK3R1 , PTEN , RB1 , RPL22 , SOS1 , TAF1 , TP53 , ZMYM2

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Histology: UCEC; Total number of genes: 382

ACTG1 , ACTN1 , ACTN2 , ACVR1 , ADGRB1 , AHCTF1 , AIFM1 , AKAP9 , ALMS1 , ANAPC1 , APAF1 , ARHGAP35 , ARHGAP5 , ARID1A , ATM , ATR , BCAR1 , BDNF , BRAF , BRCA1 , BRCA2 , BRIP1 , BTRC , BUB1B , CAB39L , CACNA1A , CACNA1B , CACNA1C , CACNA1D , CACNA1E , CACNA1F , CACNA1G , CACNA1I , CACNA1S , CACNA2D1 , CACNA2D2 , CACNA2D3 , CACNA2D4 , CACNB1 , CACNB4 , CACNG3 , CACNG7 , CAPN2 , CASP10 , CASP6 , CASP8 , CCNA2 , CCNB1 , CCNB3 , CCND1 , CCNE2 , CDC14A , CDC16 , CDC23 , CDC27 , CDC45 , CDC7 , CDK5RAP2 , CENPI , CENPJ , CEP135 , CEP164 , CEP192 , CEP250 , CEP290 , CEP72 , CEP76 , CETN2 , CHEK2 , CKAP5 , CLASP1 , CLIP1 , CNTRL , COL11A1 , COL1A1 , COL1A2 , COL2A1 , COL3A1 , COL4A1 , COL4A2 , COL4A4 , COL4A6 , COL5A1 , COL5A2 , COL5A3 , COL6A2 , COL6A3 , COL6A6 , CREB1 , CRKL , CTNNB1 , CUL1 , DCTN1 , DDB1 , DIAPH1 , DICER1 , DIDO1 , DKC1 , DNA2 , DOCK1 , DUSP10 , DYNC1H1 , DYRK1A , EGF , EIF4B , EP300 , ERBB2 , ERBB3 , ERCC3 , ERCC4 , ERCC5 , ERCC6 , ERCC6L , FANCA , FANCB , FANCD2 , FANCE , FANCG , FANCM , FAS , FASLG , FBXO5 , FBXW7 , FGF5 , FGFR2 , FLNA , FLNB , FLNC , FLT1 , FN1 , FOXO1 , FOXO4 , GORASP1 , GSK3A , GTF2H1 , HGF , HIF1A , HIST1H2BD , HIST1H2BL , HSPA6 , HSPA8 , IBSP , IGF1 , IGF1R , IKBKB , IL1RAP , IRAK3 , IRAK4 , IRS1 , ITGA1 , ITGA10 , ITGA2 , ITGA2B , ITGA3 , ITGA5 , ITGA7 , ITGA8 , ITGA9 , ITGAV , ITGB3 , ITGB4 , ITGB5 , ITGB6 , KDR , KIF18A , KIF23 , KIF2B , KIF2C , KNL1 , KNTC1 , KRAS , LAMA1 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , LAMB1 , LAMB2 , LAMB3 , LAMB4 , LAMC1 , LAMC2 , LAMC3 , LIG1 , LIG3 , LIG4 , LIN54 , LIN9 , LMNA , MAP2K4 , MAP2K6 , MAP3K1 , MAP3K13 , MAP3K14 , MAP3K2 , MAP3K4 , MAP3K5 , MAP3K8 , MAP4K1 , MAP4K3 , MAP4K4 , MAPK10 , MAPK7 , MAPK8 , MAPKAPK2 , MAPKAPK5 , MAPT , MAX , MBD4 , MCM2 , MCM4 , MCM5 , MCM6 , MCM7 , MDC1 , MECOM , MEF2C , MET , MIS18BP1 , MSH6 , MTOR , MYBL2 , MYC , MYL7 , MYLK , MYLK3 , NBN , NDC80 , NF1 , NFATC2 , NFKB1 , NFKB2 , NINL , NRAS , NTRK1 , NTRK2 , NUF2 , NUMA1 , NUP107 , NUP133 , NUP85 , OFD1 , ORC1 , ORC5 , PAK3 , PAK5 , PCM1 , PCNT , PDGFRA , PDGFRB , PHLPP1 , PIK3CA , PIK3CB , PIK3CD , PIK3CG , PIK3R1 , PIK3R3 , PIP5K1C , PLA2G2E , PLA2G4A , PLA2G6 , PLK4 , POLA1 , POLD1 , POLE , POLR2A , POLR2B , POT1 , PPM1D , PPP1R12A , PPP2R1A , PPP2R5A , PPP2R5E , PPP5C , PRKAA2 , PRKACG , PRKCA , PRKDC , PSMB10 , PSMC6 , PSMD1 , PSMD10 , PSMD3 , PSMD5 , PSME4 , PTEN , PTK2 , PTPN5 , PTPRR , RAD1 , RAD17 , RAD21 , RAD50 , RANBP2 , RAPGEF1 , RAPGEF2 , RASA1 , RASA2 , RASGRF1 , RASGRF2 , RASGRP3 , RB1 , RBBP7 , RBL1 , RBL2 , RCC2 , RELN , REV1 , REV3L , RFC5 , RICTOR , RIPK1 , ROCK1 , ROCK2 , RPA1 , RPL22 , RPS6KA2 , RPS6KA3 , RPS6KA6 , RPTOR , RRM2 , RSF1 , SDCCAG8 , SEH1L , SESN3 , SGO1 , SGO2 , SKP2 , SMARCA5 , SMC1A , SMC1B , SOS1 , SOS2 , STAG1 , STAG2 , STAG3 , STEAP3 , STK3 , STK4 , STMN1 , SUN2 , SYCP1 , SYCP2 , SYNE1 , SYNE2 , TAB2 , TAF1 , TAOK1 , TAOK2 , TFDP1 , TGFBR1 , THBS1 , THBS2 , THBS4 , TLN1 , TLN2 , TNC , TNN , TNR , TNXB , TP53 , TP53BP1 , TRAF6 , TSC1 , TUBA1A , TUBA4A , TUBG1 , TUBG2 , TUBGCP2 , TUBGCP3 , TUBGCP5 , TUBGCP6 , ULK2 , VAV3 , VTN , VWF , XAB2 , XIAP , XPO1 , XRCC5 , XRCC6 , ZMYM2

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Pathway: DRIVER_GENE; Total number of genes: 87

ACVR1 , ACVR2A , APC , ARID1A , ATM , ATR , ATRX , AXIN1 , BAP1 , BRAF , BRCA1 , CASP8 , CBFB , CCND1 , CDH1 , CDK12 , CDKN1B , CDKN2A , CIC , CREBBP , CTNNB1 , CYLD , DACH1 , DICER1 , EGFR , EP300 , EPHA2 , ERBB2 , ERBB3 , ERCC2 , FBXW7 , FGFR2 , FGFR3 , FLNA , FLT3 , GNAS , HRAS , IDH1 , IDH2 , IL6ST , KDM6A , KIT , KRAS , LATS1 , LZTR1 , MAP2K1 , MAP2K4 , MAP3K1 , MAPK1 , MECOM , MET , MGA , MSH6 , MTOR , MYH9 , NF1 , NOTCH1 , NRAS , NSD1 , NSD2 , NUP133 , PDGFRA , PIK3CA , PIK3R1 , PSIP1 , PTEN , PTPN11 , PTPRD , RAC1 , RASA1 , RB1 , RPL22 , RPS6KA3 , RUNX1 , SMAD2 , SMAD4 , SMARCA4 , SOS1 , SPTAN1 , STK11 , TAF1 , TET2 , TGFBR2 , TP53 , TSC1 , TSC2 , ZMYM2

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Pathway: KEGG_APOPTOSIS; Total number of genes: 53

AIFM1 , AKT2 , AKT3 , APAF1 , ATM , BAD , BAX , BID , BIRC2 , BIRC3 , CAPN1 , CAPN2 , CASP10 , CASP6 , CASP7 , CASP8 , CHP2 , CHUK , CSF2RB , DFFA , ENDOD1 , FAS , FASLG , IKBKB , IL1A , IL1B , IL1R1 , IL1RAP , IRAK1 , IRAK2 , IRAK3 , IRAK4 , MAP3K14 , NFKB1 , NGF , NTRK1 , PIK3CA , PIK3CB , PIK3CD , PIK3CG , PIK3R1 , PIK3R3 , PIK3R5 , PPP3CA , PPP3R2 , PRKACG , PRKAR1B , RIPK1 , TNFRSF10B , TNFRSF10D , TNFSF10 , TP53 , XIAP

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Pathway: KEGG_ECM_RECEPTOR_INTERACTION; Total number of genes: 64

COL11A1 , COL11A2 , COL1A1 , COL1A2 , COL2A1 , COL3A1 , COL4A1 , COL4A2 , COL4A4 , COL4A6 , COL5A1 , COL5A2 , COL5A3 , COL6A1 , COL6A2 , COL6A3 , COL6A6 , COMP , FN1 , IBSP , ITGA1 , ITGA10 , ITGA11 , ITGA2 , ITGA2B , ITGA3 , ITGA4 , ITGA5 , ITGA6 , ITGA7 , ITGA8 , ITGA9 , ITGAV , ITGB1 , ITGB3 , ITGB4 , ITGB5 , ITGB6 , ITGB7 , ITGB8 , LAMA1 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , LAMB1 , LAMB2 , LAMB3 , LAMB4 , LAMC1 , LAMC2 , LAMC3 , RELN , SPP1 , THBS1 , THBS2 , THBS3 , THBS4 , TNC , TNN , TNR , TNXB , VTN , VWF

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Pathway: KEGG_FOCAL_ADHESION; Total number of genes: 158

ACTB , ACTG1 , ACTN1 , ACTN2 , ACTN3 , ACTN4 , AKT2 , AKT3 , ARHGAP35 , ARHGAP5 , BAD , BCAR1 , BIRC2 , BIRC3 , BRAF , CAPN2 , CCND1 , CCND2 , COL11A1 , COL11A2 , COL1A1 , COL1A2 , COL2A1 , COL3A1 , COL4A1 , COL4A2 , COL4A4 , COL4A6 , COL5A1 , COL5A2 , COL5A3 , COL6A1 , COL6A2 , COL6A3 , COL6A6 , COMP , CRKL , CTNNB1 , DIAPH1 , DOCK1 , EGF , EGFR , ERBB2 , FLNA , FLNB , FLNC , FLT1 , FLT4 , FN1 , FYN , GRB2 , HGF , HRAS , IBSP , IGF1 , IGF1R , ITGA1 , ITGA10 , ITGA11 , ITGA2 , ITGA2B , ITGA3 , ITGA4 , ITGA5 , ITGA6 , ITGA7 , ITGA8 , ITGA9 , ITGAV , ITGB1 , ITGB3 , ITGB4 , ITGB5 , ITGB6 , ITGB7 , ITGB8 , KDR , LAMA1 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , LAMB1 , LAMB2 , LAMB3 , LAMB4 , LAMC1 , LAMC2 , LAMC3 , MAP2K1 , MAPK1 , MAPK10 , MAPK8 , MAPK9 , MET , MYL2 , MYL7 , MYLK , MYLK2 , MYLK3 , PAK2 , PAK3 , PAK5 , PAK6 , PARVA , PDGFC , PDGFD , PDGFRA , PDGFRB , PIK3CA , PIK3CB , PIK3CD , PIK3CG , PIK3R1 , PIK3R3 , PIK3R5 , PIP5K1C , PPP1R12A , PRKCA , PRKCB , PRKCG , PTEN , PTK2 , RAC1 , RAF1 , RAPGEF1 , RASGRF1 , RELN , ROCK1 , ROCK2 , SHC1 , SHC2 , SHC3 , SOS1 , SOS2 , SPP1 , SRC , THBS1 , THBS2 , THBS3 , THBS4 , TLN1 , TLN2 , TNC , TNN , TNR , TNXB , VAV1 , VAV2 , VAV3 , VCL , VEGFA , VEGFC , VEGFD , VTN , VWF , XIAP , ZYX

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Pathway: KEGG_MAPK_SIGNALING_PATHWAY; Total number of genes: 166

AKT2 , AKT3 , ATF2 , ATF4 , BDNF , BRAF , CACNA1A , CACNA1B , CACNA1C , CACNA1D , CACNA1E , CACNA1F , CACNA1G , CACNA1H , CACNA1I , CACNA1S , CACNA2D1 , CACNA2D2 , CACNA2D3 , CACNA2D4 , CACNB1 , CACNB2 , CACNB4 , CACNG3 , CACNG4 , CACNG5 , CACNG7 , CDC25B , CHP2 , CHUK , CRKL , DUSP10 , DUSP16 , EGF , EGFR , FAS , FASLG , FGF10 , FGF12 , FGF13 , FGF23 , FGF5 , FGF7 , FGFR1 , FGFR2 , FGFR3 , FGFR4 , FLNA , FLNB , FLNC , FOS , GNA12 , GRB2 , HRAS , HSPA1L , HSPA6 , HSPA8 , IKBKB , IL1A , IL1B , IL1R1 , IL1R2 , KRAS , MAP2K1 , MAP2K2 , MAP2K3 , MAP2K4 , MAP2K5 , MAP2K6 , MAP2K7 , MAP3K1 , MAP3K11 , MAP3K12 , MAP3K13 , MAP3K14 , MAP3K2 , MAP3K4 , MAP3K5 , MAP3K6 , MAP3K7 , MAP3K8 , MAP4K1 , MAP4K2 , MAP4K3 , MAP4K4 , MAPK1 , MAPK10 , MAPK13 , MAPK14 , MAPK7 , MAPK8 , MAPK8IP2 , MAPK8IP3 , MAPK9 , MAPKAPK2 , MAPKAPK3 , MAPKAPK5 , MAPT , MAX , MECOM , MEF2C , MKNK2 , MOS , MYC , NF1 , NFATC2 , NFATC4 , NFKB1 , NFKB2 , NGF , NLK , NRAS , NTF3 , NTRK1 , NTRK2 , PAK2 , PDGFRA , PDGFRB , PLA2G2E , PLA2G3 , PLA2G4A , PLA2G4E , PLA2G6 , PPM1A , PPM1B , PPP3CA , PPP3R2 , PPP5C , PRKACG , PRKCA , PRKCB , PRKCG , PTPN5 , PTPN7 , PTPRR , RAC1 , RAF1 , RAPGEF2 , RASA1 , RASA2 , RASGRF1 , RASGRF2 , RASGRP1 , RASGRP2 , RASGRP3 , RASGRP4 , RELB , RPS6KA1 , RPS6KA2 , RPS6KA3 , RPS6KA4 , RPS6KA5 , RPS6KA6 , SOS1 , SOS2 , STK3 , STK4 , STMN1 , TAB1 , TAB2 , TAOK1 , TAOK2 , TGFBR1 , TGFBR2 , TP53 , TRAF6

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Pathway: KEGG_MTOR_SIGNALING_PATHWAY; Total number of genes: 34

AKT2 , AKT3 , BRAF , CAB39L , EIF4B , HIF1A , IGF1 , MAPK1 , MTOR , PIK3CA , PIK3CB , PIK3CD , PIK3CG , PIK3R1 , PIK3R3 , PIK3R5 , PRKAA1 , PRKAA2 , RICTOR , RPS6KA1 , RPS6KA2 , RPS6KA3 , RPS6KA6 , RPS6KB1 , RPTOR , STK11 , STRADA , TSC1 , TSC2 , ULK1 , ULK2 , VEGFA , VEGFC , VEGFD

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Pathway: KEGG_P53_SIGNALING_PATHWAY; Total number of genes: 37

ADGRB1 , APAF1 , ATM , ATR , BAX , BID , CASP8 , CCNB1 , CCNB3 , CCND1 , CCND2 , CCNE2 , CDK4 , CDKN1A , CDKN2A , CHEK1 , CHEK2 , COP1 , FAS , GTSE1 , IGF1 , MDM2 , PIDD1 , PPM1D , PTEN , RRM2 , SERPINB5 , SERPINE1 , SESN2 , SESN3 , SFN , SIAH1 , STEAP3 , THBS1 , TNFRSF10B , TP53 , TSC2

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Pathway: KEGG_TGF_BETA_SIGNALING_PATHWAY; Total number of genes: 18

COMP , CUL1 , E2F5 , MAPK1 , MYC , PPP2R1A , RBL1 , RBL2 , ROCK1 , ROCK2 , RPS6KB1 , TFDP1 , TGFBR1 , TGFBR2 , THBS1 , THBS2 , THBS3 , THBS4

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Pathway: REACTOME_CELL_CYCLE; Total number of genes: 196

ACD , ACTR1A , AHCTF1 , AKAP9 , ALMS1 , ANAPC1 , ANAPC2 , ANAPC4 , ATM , ATR , BRCA1 , BTRC , BUB1 , BUB1B , CCNA1 , CCNA2 , CCNB1 , CCND1 , CCND2 , CCNE2 , CDC14A , CDC16 , CDC23 , CDC25B , CDC27 , CDC45 , CDC6 , CDC7 , CDK4 , CDK5RAP2 , CDKN1A , CDKN1B , CDKN2A , CENPI , CENPJ , CENPP , CEP131 , CEP135 , CEP164 , CEP192 , CEP250 , CEP290 , CEP57 , CEP63 , CEP72 , CEP76 , CETN2 , CHEK1 , CHEK2 , CKAP5 , CLASP1 , CLIP1 , CNTRL , COP1 , CUL1 , DCTN1 , DCTN2 , DIDO1 , DKC1 , DNA2 , DSN1 , DYNC1H1 , DYNC1I2 , DYRK1A , E2F1 , E2F5 , ERCC6L , FBXO5 , GORASP1 , HDAC1 , HIST1H2AC , HIST1H2BD , HIST1H2BL , HIST1H2BN , HIST2H2AC , HJURP , HSP90AA1 , INCENP , KIF18A , KIF20A , KIF23 , KIF2A , KIF2B , KIF2C , KNL1 , KNTC1 , LIG1 , LIN54 , LIN9 , LMNA , MAX , MCM10 , MCM2 , MCM3 , MCM4 , MCM5 , MCM6 , MCM7 , MCM8 , MDM2 , MIS18BP1 , MYBL2 , MYC , NDC80 , NEDD1 , NEK2 , NINL , NUF2 , NUMA1 , NUP107 , NUP133 , NUP85 , OFD1 , ORC1 , ORC5 , PAFAH1B1 , PCM1 , PCNT , PLK4 , POLA1 , POLA2 , POLD1 , POLE , POT1 , PPP2R1A , PPP2R2A , PPP2R5A , PPP2R5C , PPP2R5E , PRIM2 , PSMA4 , PSMA8 , PSMB10 , PSMC2 , PSMC6 , PSMD1 , PSMD10 , PSMD12 , PSMD3 , PSMD5 , PSME4 , RAD1 , RAD17 , RAD21 , RAD9A , RANBP2 , RANGAP1 , RB1 , RBBP7 , RBL1 , RBL2 , RCC2 , REC8 , RFC5 , RPA1 , RRM2 , RSF1 , RUVBL1 , RUVBL2 , SDCCAG8 , SEH1L , SGO1 , SGO2 , SKA1 , SKP2 , SMARCA5 , SMC1A , SMC1B , SMC3 , SPC25 , STAG1 , STAG2 , STAG3 , SUN2 , SYCP1 , SYCP2 , SYNE1 , SYNE2 , TAOK1 , TERF2 , TERT , TFDP1 , TP53 , TUBA1A , TUBA4A , TUBB4A , TUBG1 , TUBG2 , TUBGCP2 , TUBGCP3 , TUBGCP5 , TUBGCP6 , WRAP53 , XPO1 , ZW10 , ZWINT

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Pathway: REACTOME_DNA_REPAIR; Total number of genes: 44

ATM , ATR , BRCA1 , BRCA2 , BRIP1 , DDB1 , ERCC2 , ERCC3 , ERCC4 , ERCC5 , ERCC6 , FANCA , FANCB , FANCD2 , FANCE , FANCG , FANCM , GTF2H1 , LIG1 , LIG3 , LIG4 , MBD4 , MDC1 , MRE11 , NBN , PALB2 , POLD1 , POLE , POLR2A , POLR2B , PRKDC , RAD23B , RAD50 , REV1 , REV3L , RFC5 , RPA1 , TDP1 , TP53BP1 , USP1 , XAB2 , XPC , XRCC5 , XRCC6

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Pathway: REACTOME_PI3K_AKT_ACTIVATION; Total number of genes: 22

AKT2 , AKT3 , BAD , CDKN1A , CDKN1B , CHUK , CREB1 , FOXO1 , FOXO4 , GSK3A , IRS1 , MDM2 , MTOR , NGF , NTRK1 , PHLPP1 , PIK3CA , PIK3CB , PIK3R1 , PTEN , RICTOR , TSC2

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Total number of genes: 623

ACD , ACTB , ACTG1 , ACTN1 , ACTN2 , ACTN3 , ACTN4 , ACTR1A , ACVR1 , ACVR2A , ADGRB1 , AHCTF1 , AIFM1 , AKAP9 , AKT2 , AKT3 , ALMS1 , ANAPC1 , ANAPC2 , ANAPC4 , APAF1 , APC , ARHGAP35 , ARHGAP5 , ARID1A , ATF2 , ATF4 , ATM , ATR , ATRX , AXIN1 , BAD , BAP1 , BAX , BCAR1 , BDNF , BID , BIRC2 , BIRC3 , BRAF , BRCA1 , BRCA2 , BRIP1 , BTRC , BUB1 , BUB1B , CAB39L , CACNA1A , CACNA1B , CACNA1C , CACNA1D , CACNA1E , CACNA1F , CACNA1G , CACNA1H , CACNA1I , CACNA1S , CACNA2D1 , CACNA2D2 , CACNA2D3 , CACNA2D4 , CACNB1 , CACNB2 , CACNB4 , CACNG3 , CACNG4 , CACNG5 , CACNG7 , CAPN1 , CAPN2 , CASP10 , CASP6 , CASP7 , CASP8 , CBFB , CCNA1 , CCNA2 , CCNB1 , CCNB3 , CCND1 , CCND2 , CCNE2 , CDC14A , CDC16 , CDC23 , CDC25B , CDC27 , CDC45 , CDC6 , CDC7 , CDH1 , CDK12 , CDK4 , CDK5RAP2 , CDKN1A , CDKN1B , CDKN2A , CENPI , CENPJ , CENPP , CEP131 , CEP135 , CEP164 , CEP192 , CEP250 , CEP290 , CEP57 , CEP63 , CEP72 , CEP76 , CETN2 , CHEK1 , CHEK2 , CHP2 , CHUK , CIC , CKAP5 , CLASP1 , CLIP1 , CNTRL , COL11A1 , COL11A2 , COL1A1 , COL1A2 , COL2A1 , COL3A1 , COL4A1 , COL4A2 , COL4A4 , COL4A6 , COL5A1 , COL5A2 , COL5A3 , COL6A1 , COL6A2 , COL6A3 , COL6A6 , COMP , COP1 , CREB1 , CREBBP , CRKL , CSF2RB , CTNNB1 , CUL1 , CYLD , DACH1 , DCTN1 , DCTN2 , DDB1 , DFFA , DIAPH1 , DICER1 , DIDO1 , DKC1 , DNA2 , DOCK1 , DSN1 , DUSP10 , DUSP16 , DYNC1H1 , DYNC1I2 , DYRK1A , E2F1 , E2F5 , EGF , EGFR , EIF4B , ENDOD1 , EP300 , EPHA2 , ERBB2 , ERBB3 , ERCC2 , ERCC3 , ERCC4 , ERCC5 , ERCC6 , ERCC6L , FANCA , FANCB , FANCD2 , FANCE , FANCG , FANCM , FAS , FASLG , FBXO5 , FBXW7 , FGF10 , FGF12 , FGF13 , FGF23 , FGF5 , FGF7 , FGFR1 , FGFR2 , FGFR3 , FGFR4 , FLNA , FLNB , FLNC , FLT1 , FLT3 , FLT4 , FN1 , FOS , FOXO1 , FOXO4 , FYN , GNA12 , GNAS , GORASP1 , GRB2 , GSK3A , GTF2H1 , GTSE1 , HDAC1 , HGF , HIF1A , HIST1H2AC , HIST1H2BD , HIST1H2BL , HIST1H2BN , HIST2H2AC , HJURP , HRAS , HSP90AA1 , HSPA1L , HSPA6 , HSPA8 , IBSP , IDH1 , IDH2 , IGF1 , IGF1R , IKBKB , IL1A , IL1B , IL1R1 , IL1R2 , IL1RAP , IL6ST , INCENP , IRAK1 , IRAK2 , IRAK3 , IRAK4 , IRS1 , ITGA1 , ITGA10 , ITGA11 , ITGA2 , ITGA2B , ITGA3 , ITGA4 , ITGA5 , ITGA6 , ITGA7 , ITGA8 , ITGA9 , ITGAV , ITGB1 , ITGB3 , ITGB4 , ITGB5 , ITGB6 , ITGB7 , ITGB8 , KDM6A , KDR , KIF18A , KIF20A , KIF23 , KIF2A , KIF2B , KIF2C , KIT , KNL1 , KNTC1 , KRAS , LAMA1 , LAMA2 , LAMA3 , LAMA4 , LAMA5 , LAMB1 , LAMB2 , LAMB3 , LAMB4 , LAMC1 , LAMC2 , LAMC3 , LATS1 , LIG1 , LIG3 , LIG4 , LIN54 , LIN9 , LMNA , LZTR1 , MAP2K1 , MAP2K2 , MAP2K3 , MAP2K4 , MAP2K5 , MAP2K6 , MAP2K7 , MAP3K1 , MAP3K11 , MAP3K12 , MAP3K13 , MAP3K14 , MAP3K2 , MAP3K4 , MAP3K5 , MAP3K6 , MAP3K7 , MAP3K8 , MAP4K1 , MAP4K2 , MAP4K3 , MAP4K4 , MAPK1 , MAPK10 , MAPK13 , MAPK14 , MAPK7 , MAPK8 , MAPK8IP2 , MAPK8IP3 , MAPK9 , MAPKAPK2 , MAPKAPK3 , MAPKAPK5 , MAPT , MAX , MBD4 , MCM10 , MCM2 , MCM3 , MCM4 , MCM5 , MCM6 , MCM7 , MCM8 , MDC1 , MDM2 , MECOM , MEF2C , MET , MGA , MIS18BP1 , MKNK2 , MOS , MRE11 , MSH6 , MTOR , MYBL2 , MYC , MYH9 , MYL2 , MYL7 , MYLK , MYLK2 , MYLK3 , NBN , NDC80 , NEDD1 , NEK2 , NF1 , NFATC2 , NFATC4 , NFKB1 , NFKB2 , NGF , NINL , NLK , NOTCH1 , NRAS , NSD1 , NSD2 , NTF3 , NTRK1 , NTRK2 , NUF2 , NUMA1 , NUP107 , NUP133 , NUP85 , OFD1 , ORC1 , ORC5 , PAFAH1B1 , PAK2 , PAK3 , PAK5 , PAK6 , PALB2 , PARVA , PCM1 , PCNT , PDGFC , PDGFD , PDGFRA , PDGFRB , PHLPP1 , PIDD1 , PIK3CA , PIK3CB , PIK3CD , PIK3CG , PIK3R1 , PIK3R3 , PIK3R5 , PIP5K1C , PLA2G2E , PLA2G3 , PLA2G4A , PLA2G4E , PLA2G6 , PLK4 , POLA1 , POLA2 , POLD1 , POLE , POLR2A , POLR2B , POT1 , PPM1A , PPM1B , PPM1D , PPP1R12A , PPP2R1A , PPP2R2A , PPP2R5A , PPP2R5C , PPP2R5E , PPP3CA , PPP3R2 , PPP5C , PRIM2 , PRKAA1 , PRKAA2 , PRKACG , PRKAR1B , PRKCA , PRKCB , PRKCG , PRKDC , PSIP1 , PSMA4 , PSMA8 , PSMB10 , PSMC2 , PSMC6 , PSMD1 , PSMD10 , PSMD12 , PSMD3 , PSMD5 , PSME4 , PTEN , PTK2 , PTPN11 , PTPN5 , PTPN7 , PTPRD , PTPRR , RAC1 , RAD1 , RAD17 , RAD21 , RAD23B , RAD50 , RAD9A , RAF1 , RANBP2 , RANGAP1 , RAPGEF1 , RAPGEF2 , RASA1 , RASA2 , RASGRF1 , RASGRF2 , RASGRP1 , RASGRP2 , RASGRP3 , RASGRP4 , RB1 , RBBP7 , RBL1 , RBL2 , RCC2 , REC8 , RELB , RELN , REV1 , REV3L , RFC5 , RICTOR , RIPK1 , ROCK1 , ROCK2 , RPA1 , RPL22 , RPS6KA1 , RPS6KA2 , RPS6KA3 , RPS6KA4 , RPS6KA5 , RPS6KA6 , RPS6KB1 , RPTOR , RRM2 , RSF1 , RUNX1 , RUVBL1 , RUVBL2 , SDCCAG8 , SEH1L , SERPINB5 , SERPINE1 , SESN2 , SESN3 , SFN , SGO1 , SGO2 , SHC1 , SHC2 , SHC3 , SIAH1 , SKA1 , SKP2 , SMAD2 , SMAD4 , SMARCA4 , SMARCA5 , SMC1A , SMC1B , SMC3 , SOS1 , SOS2 , SPC25 , SPP1 , SPTAN1 , SRC , STAG1 , STAG2 , STAG3 , STEAP3 , STK11 , STK3 , STK4 , STMN1 , STRADA , SUN2 , SYCP1 , SYCP2 , SYNE1 , SYNE2 , TAB1 , TAB2 , TAF1 , TAOK1 , TAOK2 , TDP1 , TERF2 , TERT , TET2 , TFDP1 , TGFBR1 , TGFBR2 , THBS1 , THBS2 , THBS3 , THBS4 , TLN1 , TLN2 , TNC , TNFRSF10B , TNFRSF10D , TNFSF10 , TNN , TNR , TNXB , TP53 , TP53BP1 , TRAF6 , TSC1 , TSC2 , TUBA1A , TUBA4A , TUBB4A , TUBG1 , TUBG2 , TUBGCP2 , TUBGCP3 , TUBGCP5 , TUBGCP6 , ULK1 , ULK2 , USP1 , VAV1 , VAV2 , VAV3 , VCL , VEGFA , VEGFC , VEGFD , VTN , VWF , WRAP53 , XAB2 , XIAP , XPC , XPO1 , XRCC5 , XRCC6 , ZMYM2 , ZW10 , ZWINT , ZYX

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Histoloty: all; Total number of genes: 87

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Histoloty: UCEC; Total number of genes: 50

ACVR1 , ACVR1 , ARID1A , ARID1A , ATM , ATM , ATR , ATR , CCND1 , CCND1 , CTNNB1 , CTNNB1 , DICER1 , DICER1 , EP300 , EP300 , ERBB2 , ERBB2 , ERBB3 , ERBB3 , FBXW7 , FBXW7 , FGFR2 , FGFR2 , KRAS , KRAS , MAP3K1 , MAP3K1 , MSH6 , MSH6 , NRAS , NRAS , PIK3CA , PIK3CA , PIK3R1 , PIK3R1 , PTEN , PTEN , RB1 , RB1 , RPL22 , RPL22 , SOS1 , SOS1 , TAF1 , TAF1 , TP53 , TP53 , ZMYM2 , ZMYM2

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Histoloty: COADREAD; Total number of genes: 20

ACVR2A , ACVR2A , APC , APC , ARID1A , ARID1A , FBXW7 , FBXW7 , GNAS , GNAS , KRAS , KRAS , PIK3CA , PIK3CA , SMAD2 , SMAD2 , SMAD4 , SMAD4 , TP53 , TP53

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Histoloty: LIHC; Total number of genes: 32

ACVR2A , ACVR2A , ARID1A , ARID1A , AXIN1 , AXIN1 , BAP1 , BAP1 , CDKN2A , CDKN2A , CTNNB1 , CTNNB1 , IDH1 , IDH1 , IL6ST , IL6ST , KRAS , KRAS , NSD2 , NSD2 , NUP133 , NUP133 , PIK3CA , PIK3CA , RB1 , RB1 , RPS6KA3 , RPS6KA3 , TP53 , TP53 , TSC2 , TSC2

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Histoloty: PRAD; Total number of genes: 12

APC , APC , CTNNB1 , CTNNB1 , IDH1 , IDH1 , PIK3CA , PIK3CA , PTEN , PTEN , TP53 , TP53

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Histoloty: LUAD; Total number of genes: 28

ARID1A , ARID1A , ATM , ATM , BRAF , BRAF , CTNNB1 , CTNNB1 , EGFR , EGFR , KRAS , KRAS , MET , MET , MGA , MGA , NF1 , NF1 , PIK3CA , PIK3CA , RB1 , RB1 , SMARCA4 , SMARCA4 , STK11 , STK11 , TP53 , TP53

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Histoloty: CESC; Total number of genes: 26

ARID1A , ARID1A , EP300 , EP300 , ERBB3 , ERBB3 , FBXW7 , FBXW7 , KRAS , KRAS , LATS1 , LATS1 , MAPK1 , MAPK1 , NOTCH1 , NOTCH1 , PIK3CA , PIK3CA , PTEN , PTEN , RB1 , RB1 , TGFBR2 , TGFBR2 , TP53 , TP53

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Histoloty: LGG; Total number of genes: 28

ARID1A , ARID1A , ATRX , ATRX , CIC , CIC , EGFR , EGFR , IDH1 , IDH1 , IDH2 , IDH2 , NF1 , NF1 , NOTCH1 , NOTCH1 , PIK3CA , PIK3CA , PIK3R1 , PIK3R1 , PTEN , PTEN , PTPN11 , PTPN11 , SMARCA4 , SMARCA4 , TP53 , TP53

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Histoloty: PAAD; Total number of genes: 16

ARID1A , ARID1A , CDKN2A , CDKN2A , GNAS , GNAS , KDM6A , KDM6A , KRAS , KRAS , SMAD4 , SMAD4 , TGFBR2 , TGFBR2 , TP53 , TP53

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Histoloty: BLCA; Total number of genes: 34

ARID1A , ARID1A , ATM , ATM , CDKN2A , CDKN2A , CREBBP , CREBBP , EP300 , EP300 , ERBB2 , ERBB2 , ERBB3 , ERBB3 , ERCC2 , ERCC2 , FBXW7 , FBXW7 , FGFR3 , FGFR3 , KDM6A , KDM6A , PIK3CA , PIK3CA , PSIP1 , PSIP1 , RB1 , RB1 , SPTAN1 , SPTAN1 , TP53 , TP53 , TSC1 , TSC1

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Histoloty: BRCA; Total number of genes: 36

ARID1A , ARID1A , BRCA1 , BRCA1 , CASP8 , CASP8 , CBFB , CBFB , CDH1 , CDH1 , CDKN1B , CDKN1B , ERBB2 , ERBB2 , FBXW7 , FBXW7 , MAP2K4 , MAP2K4 , MAP3K1 , MAP3K1 , NF1 , NF1 , PIK3CA , PIK3CA , PIK3R1 , PIK3R1 , PTEN , PTEN , PTPRD , PTPRD , RB1 , RB1 , RUNX1 , RUNX1 , TP53 , TP53

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Histoloty: KIRC; Total number of genes: 12

ATM , ATM , BAP1 , BAP1 , MTOR , MTOR , PIK3CA , PIK3CA , PTEN , PTEN , TP53 , TP53

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Histoloty: GBM; Total number of genes: 22

ATRX , ATRX , EGFR , EGFR , IDH1 , IDH1 , LZTR1 , LZTR1 , NF1 , NF1 , PDGFRA , PDGFRA , PIK3CA , PIK3CA , PIK3R1 , PIK3R1 , PTEN , PTEN , RB1 , RB1 , TP53 , TP53

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Histoloty: SKCM; Total number of genes: 28

BRAF , BRAF , CDKN2A , CDKN2A , CTNNB1 , CTNNB1 , DACH1 , DACH1 , IDH1 , IDH1 , KIT , KIT , MAP2K1 , MAP2K1 , MECOM , MECOM , NF1 , NF1 , NRAS , NRAS , PTEN , PTEN , RAC1 , RAC1 , RB1 , RB1 , TP53 , TP53

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Histoloty: THCA; Total number of genes: 6

BRAF , BRAF , HRAS , HRAS , NRAS , NRAS

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Histoloty: HNSC; Total number of genes: 42

CASP8 , CASP8 , CDKN2A , CDKN2A , CYLD , CYLD , EP300 , EP300 , EPHA2 , EPHA2 , FBXW7 , FBXW7 , FGFR3 , FGFR3 , FLNA , FLNA , HRAS , HRAS , KDM6A , KDM6A , MAPK1 , MAPK1 , MYH9 , MYH9 , NOTCH1 , NOTCH1 , NSD1 , NSD1 , PIK3CA , PIK3CA , PTEN , PTEN , RAC1 , RAC1 , RASA1 , RASA1 , RB1 , RB1 , TGFBR2 , TGFBR2 , TP53 , TP53

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Histoloty: OV; Total number of genes: 8

CDK12 , CDK12 , NF1 , NF1 , RB1 , RB1 , TP53 , TP53

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Histoloty: LUSC; Total number of genes: 14

CDKN2A , CDKN2A , NF1 , NF1 , PIK3CA , PIK3CA , PTEN , PTEN , RASA1 , RASA1 , RB1 , RB1 , TP53 , TP53

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Histoloty: LAML; Total number of genes: 14

FLT3 , FLT3 , IDH2 , IDH2 , KIT , KIT , PTPN11 , PTPN11 , RUNX1 , RUNX1 , TET2 , TET2 , TP53 , TP53

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Total number of genes: 87

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